Original Research ARTICLE
Reference genome anchoring of high density markers for association mapping and genomic prediction in European winter wheat
- 1National Institute of Agricultural Botany (NIAB), United Kingdom
- 2IMplant Consultancy Ltd., United Kingdom
- 3Kansas State University, United States
- 4Biogemma (France), France
- 5University of Cambridge, United Kingdom
In this study, we anchored genotyping-by-sequencing data to the International Wheat Genome Sequencing Consortium Reference Sequence v1.0 assembly to generate over 40,000 high quality single nucleotide polymorphism markers on a panel of 376 elite European winter wheat varieties released between 1946 and 2007. We compared association mapping and genomic prediction accuracy for a range of productivity traits with previous results based on lower density dominant DArT markers. The results demonstrate that the availability of RefSeq v1.0 supports higher precision trait mapping and provides the density of markers required to obtain accurate predictions of traits controlled by multiple small effect loci, including grain yield.
Keywords: Mapping, quantitative genetics, Trait dissection, Next-generating sequencing, genomic selection
Received: 02 Nov 2018;
Accepted: 12 Sep 2019.
Copyright: © 2019 Ladejobi, Mackay, Poland, Praud, Hibberd and Bentley. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Dr. Alison R. Bentley, National Institute of Agricultural Botany (NIAB), Cambridge, CB3 0LE UK, England, United Kingdom, email@example.com