Frontiers in Cell and Developmental Biology | Molecular and Cellular Pathology

Original Research

Published on 28 Jul 2025

Altered endoplasmic reticulum calcium loading in human PLN-R14del cardiomyopathy

in Molecular and Cellular Pathology

Willem Borbein
Lukas Dahmlos
Umber Saleem
Marina Reinsch
Ingke Braren
Thomas Schulze
Birgit Klampe
Friederike Cuello
Justus Stenzig
Thomas Eschenhagen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1627985

1,901 views
1 citation

Original Research

Published on 24 Jul 2025

Automated detection of diabetic retinopathy lesions in ultra-widefield fundus images using an attention-augmented YOLOv8 framework

in Molecular and Cellular Pathology

Lei-Si Hu
Jie Wang
Heng-Ming Zhang
Hai-Yu Huang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1608580

1,764 views

Original Research

Published on 23 Jul 2025

Saliva-derived exosomes regulate fibroblast metabolic reprogramming in skin wound healing

in Molecular and Cellular Pathology

Sijia Song
Rong Xiang
Siyu Chen
Jianbo Wu
Wenxia Chen
Xianyu Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1606716

2,771 views

Original Research

Published on 23 Jul 2025

Association of gastroesophageal reflux disease with the incidence of pulmonary disease

in Molecular and Cellular Pathology

Xin Wang
Yan Wang
Yijie Bu
Yu Liu
Sheng Gong
Guowei Che

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1552126

4,501 views

Editorial

Published on 23 Jul 2025

Editorial: Current trends in muscle diseases and their treatment strategies

in Molecular and Cellular Pathology

Zihang Guo
Shoulong Deng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1660074

1,675 views

Original Research

Published on 23 Jul 2025

Multimodal reasoning agent for enhanced ophthalmic decision-making: a preliminary real-world clinical validation

in Molecular and Cellular Pathology

Yijing Zhuang
Dong Fang
Pengfeng Li
Bingyu Bai
Xiangqing Hei
Lujia Feng
Wangting Li
Shaochong Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1642539

2,263 views

Review

Published on 22 Jul 2025

Characteristics and advances in signaling pathways, cellular communication, cell junctions, and oxidative stress in lymphedema

in Molecular and Cellular Pathology

Qiancheng Zhao
Zhipu Niu
Ying Pan
Yongqi Hao
Yuan Ma
Jiankai Zhao
Jianshi Du
Yiming Yang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1521320

2,713 views

Review

Published on 21 Jul 2025

Dynamic crosstalk between HSCs and liver microenvironment: multicellular interactions in the regulation of liver fibrosis

in Molecular and Cellular Pathology

Luping Wang
Yi Huang
Jingrong Chen
Jialu Gao
Sihan Chen
Mingqi Zhao
Jiguo Lin
Shunqing Zhou
Yannan Shen
Yunyun Cheng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1635763

3,095 views
1 citation

Review

Published on 18 Jul 2025

miRNAs and exosomes in psoriasis: coordinating cytoskeleton dynamics and extracellular matrix remodeling

in Molecular and Cellular Pathology

Sijing Li
Zamri Chik
Farid Nazer Faruqu
Najihah Mohd Hashim
Nor Saadah Mohd Yusof
Jennifer Fernandez Alarcon
Noraini Ahmad

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1608902

2,622 views

Methods

Published on 18 Jul 2025

Optimizing chromosome dispersion quality: the key role of cell density

in Molecular and Cellular Pathology

Chao-Xian Gao
Li-Mei Li
Yu-Ting Chen
Ying-Yan Guo
Bo-Xin Li
Xue-Qin Yang
Chang-Ye Hui

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1636498

1,361 views

Original Research

Published on 17 Jul 2025

Deep learning-based classification of multiple fundus diseases using ultra-widefield images

in Molecular and Cellular Pathology

Ming-Ming Duan
Xiang Tu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1630667

2,572 views
1 citation

Original Research

Published on 17 Jul 2025

Profiling the impact of different tau species on glial cell biology

in Molecular and Cellular Pathology

Ines Arribas Gomez
Yan Yan
Meredith T. Lilley
Yunfei Chen
Lillian M. Daughrity
Ana Moreno Arnas
Ji Shi
Jennifer M. Kachergus
E. Aubrey Thompson
Karen Jansen-West

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1622138

2,226 views

Original Research

Published on 17 Jul 2025

Standardized conversion model for retinal thickness measurements between spectral-domain and swept-source optical coherence tomography based on machine learning

in Molecular and Cellular Pathology

Zhongping Tian
Yinning Guo
Xi Chen
Qifeng Zhou
Yuan Liu
Zhizhu Yi
Li Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1612455

1,261 views

Original Research

Published on 17 Jul 2025

Epiplakin expression is lost in psoriatic skin lesions and is downregulated by IFN-γ in ex vivo skin cultures

in Molecular and Cellular Pathology

Hannes Kühtreiber
Corinne Drexler
Melanie Salek
Lisa Auer
Johannes Griss
Michael Mildner
Peter Fuchs

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1617737

2,408 views

Original Research

Published on 16 Jul 2025

Revealing age-related changes in the intraocular microenvironment and senescence modulators using aqueous humor proteomics and machine learning

in Molecular and Cellular Pathology

Xiaosheng Huang
Tiansheng Chou
Xinhua Liu
Kun Zeng
Liangnan Sun
Zonghui Yan
Shaoyi Mei
Wenqun Xi
Zongyi Zhan
Yi Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1583330

2,610 views

Review

Published on 15 Jul 2025

Oxidative stress in pediatric diseases associated with the origin of life and growth and development

in Molecular and Cellular Pathology

Bo Zheng
Jianhua Fu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1550765

1,312 views

Review

Published on 15 Jul 2025

Advances in the comprehensive mechanisms, diagnosis, and treatment of heatstroke-induced coagulopathy

in Molecular and Cellular Pathology

Chuhan Xiang
Ling Gao
Xuhui Liu
Jun Xiang
Bin Zhu
Shihui Fu
Jianhui Zhao
Qing Song

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1596039

2,259 views

Original Research

Published on 09 Jul 2025

Using deep learning to screen OCTA images for hypertension to reduce the risk of serious complications

in Molecular and Cellular Pathology

Yiheng Ding
Ziqiang Wei
Chaoyun Wang
Xinyue Li
Bingbing Li
Xueting Liu
Zhijie Fu
Hongwei Mo
Hong Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1581785

1,418 views

Original Research

Published on 07 Jul 2025

Evaluating multiple large language models on orbital diseases

in Molecular and Cellular Pathology

Qi-Chen Yang
Yan-Mei Zeng
Hong Wei
Cheng Chen
Qian Ling
Xiao-Yu Wang
Xu Chen
Yi Shao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1574378

1,904 views

Review

Published on 07 Jul 2025

The vascular endothelium as decision maker in lung injury

in Molecular and Cellular Pathology

Diana Klein

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1564627

2,577 views
2 citations

Original Research

Published on 03 Jul 2025

Temporal dynamics of gene and protein signatures following volumetric muscle loss

in Molecular and Cellular Pathology

Ishita Jain
Beu P. Oropeza
Caroline Hu
Gladys Chiang
Sree Aravindan
Renato Reyes
Daniel Yuhang Li
Paul Cheng
Ngan F. Huang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1606609

1,940 views
1 citation

Original Research

Published on 02 Jul 2025

Overexpression of GDF15 protects kidneys from ischemia reperfusion injury and affects circular RNA expression

in Molecular and Cellular Pathology

Cuilin Zhu
Qing Liu
Yale Su
Yixin Zhang
Aanal Patel
Adam Greasley
Jifu Jiang
Douglas Quan
Weiping Min
Kexiang Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1577625

2,369 views

Editorial

Published on 02 Jul 2025

Editorial: Electric stimulation in the eye and brain: advancements and applications

in Molecular and Cellular Pathology

Daisy Y. Shu
Yukari Nakano
Kin-Sang Cho
Anton Lennikov

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1643111

1,574 views

Brief Research Report

Published on 02 Jul 2025

POU5F1 bridges Hedgehog signaling and epithelial remodeling in COPD

in Molecular and Cellular Pathology

Laure M. G. Petit
Randa Belgacemi
Pauline Mulette
Audrey Brisebarre
Lynda Saber Cherif
Maëva A. Devilliers
Sarah Hatoum
Julien Ancel
Gonzague Delepine
Anne Durlach

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1566251

1,642 views

2,453 articles

articles

Altered endoplasmic reticulum calcium loading in human PLN-R14del cardiomyopathy

Automated detection of diabetic retinopathy lesions in ultra-widefield fundus images using an attention-augmented YOLOv8 framework

Saliva-derived exosomes regulate fibroblast metabolic reprogramming in skin wound healing

Association of gastroesophageal reflux disease with the incidence of pulmonary disease

Editorial: Current trends in muscle diseases and their treatment strategies

Multimodal reasoning agent for enhanced ophthalmic decision-making: a preliminary real-world clinical validation

Characteristics and advances in signaling pathways, cellular communication, cell junctions, and oxidative stress in lymphedema

Dynamic crosstalk between HSCs and liver microenvironment: multicellular interactions in the regulation of liver fibrosis

miRNAs and exosomes in psoriasis: coordinating cytoskeleton dynamics and extracellular matrix remodeling

Optimizing chromosome dispersion quality: the key role of cell density

Deep learning-based classification of multiple fundus diseases using ultra-widefield images

Profiling the impact of different tau species on glial cell biology

Standardized conversion model for retinal thickness measurements between spectral-domain and swept-source optical coherence tomography based on machine learning

Epiplakin expression is lost in psoriatic skin lesions and is downregulated by IFN-γ in ex vivo skin cultures

Revealing age-related changes in the intraocular microenvironment and senescence modulators using aqueous humor proteomics and machine learning

Oxidative stress in pediatric diseases associated with the origin of life and growth and development

Advances in the comprehensive mechanisms, diagnosis, and treatment of heatstroke-induced coagulopathy

Using deep learning to screen OCTA images for hypertension to reduce the risk of serious complications

Evaluating multiple large language models on orbital diseases

The vascular endothelium as decision maker in lung injury

Temporal dynamics of gene and protein signatures following volumetric muscle loss

Overexpression of GDF15 protects kidneys from ischemia reperfusion injury and affects circular RNA expression

Editorial: Electric stimulation in the eye and brain: advancements and applications

POU5F1 bridges Hedgehog signaling and epithelial remodeling in COPD