Frontiers in Chemistry

Original Research

Accepted on 23 May 2025

Integrative Computational Approaches Identify Haptoglobin Inhibitors to Modulate Erythrocyte Sedimentation Rate in Trauma-Linked

in Theoretical and Computational Chemistry

Abdulaziz Al Khzem
Shaban Ahmad

Frontiers in Chemistry

doi 10.3389/fchem.2025.1611972

175 views

Original Research

Accepted on 22 May 2025

Engineering the Mechanical Characteristics of Regenerated Silk Fibroin Materials: The Impact of Chemical and Physical Modification Strategies

in Polymer Chemistry

Haitao Guan
Fang Ding
Ye Xue
Jinli Zhao

Frontiers in Chemistry

doi 10.3389/fchem.2025.1606995

118 views

Original Research

Published on 22 May 2025

Design of novel pyrazole and benzofuran-based derivatives as potent acetylcholinesterase inhibitors for Alzheimer’s disease management

in Theoretical and Computational Chemistry

Mohamed El Fadili
Amine Ez-Zoubi
Mourad Aloui
Somdutt Mujwar
Hatem A. Abuelizz
Menana Elhalaoui
Adnan Amin

Frontiers in Chemistry

doi 10.3389/fchem.2025.1614462

813 views

Original Research

Published on 22 May 2025

Inhibitory effect of Fisetin against the aggregation process of SOD1 E100K mutant: computer-based drug design as a potential therapeutic for ALS disease

in Theoretical and Computational Chemistry

Fatemeh Sadat Seyedi Asl
Nasrin Malverdi
Fatemeh Sadat Ataei Kachouei
Fatemeh Zarei
Shamim Ghiabi
Payam Baziyar
Mohsen Nabi-Afjadi

Frontiers in Chemistry

doi 10.3389/fchem.2025.1569777

677 views

Original Research

Published on 21 May 2025

Synthesis and characterization of thymol-derived phenoxy acetamide derivatives using DFT, molecular docking, and parasitological investigations

in Medicinal and Pharmaceutical Chemistry

Ahmed R. Rabee
Saied M. Soliman
Hamida Abdel-Hamid
Esraa A. Moneer
Sara H. Akl
Yahya H. Shahin
Aliaa A. Masoud
Doaa Ahmad Ghareeb
Mariusz Jaremko
Abdul-Hamid Emwas

Frontiers in Chemistry

doi 10.3389/fchem.2025.1579923

8,854 views

Original Research

Published on 21 May 2025

Exploring the application of the microbial pigment violacein as a sustainable probe molecule for recycled paper-based SERS substrates

in Green and Sustainable Chemistry

Alessia Tropea
Donatella Spadaro
Dario Giuffrida
Sebastiano Trusso
Daniele Giuffrida
Tania Maria Grazia Salerno
Julio Montanez
Lourdes Morales-Oyervides
Luigi Mondello
Rosina Celeste Ponterio

Frontiers in Chemistry

doi 10.3389/fchem.2025.1571986

669 views

Original Research

Accepted on 20 May 2025

Phomaderide, a Unique (6/5/4/5/6) Spiro-Cyclic Dimmer from the Desert Plant Endophytic Fungus Phoma betae A. B. Frank (Didymellaceae)

in Medicinal and Pharmaceutical Chemistry

Haodi Sun
Yan-Duo Wang
Hui-Qi Fang
Jian Yang
Yutong Hua
Gang Ding
Lanping Guo

Frontiers in Chemistry

doi 10.3389/fchem.2025.1583666

148 views

Correction

Published on 20 May 2025

Corrigendum: Viral mimicry as a design template for nucleic acid nanocarriers

in Nanoscience

Ina F. de la Fuente
Shraddha S. Sawant
Mark Q. Tolentino
Patrick M. Corrigan
Jessica L. Rouge

Frontiers in Chemistry

doi 10.3389/fchem.2025.1624509

319 views

Perspective

Accepted on 19 May 2025

Non-Covalent Interactions in MOFs: A Quantum Approach to Gas Adsorption and Molecular Encapsulation

in Porous Crystalline Networks

Erika Medel
Rubicelia Vargas

Frontiers in Chemistry

doi 10.3389/fchem.2025.1579977

178 views

Mini Review

Accepted on 19 May 2025

Effects of Fluorine Modification on the Photocatalytic Hydrogen Production Performance of TiO2

in Green and Sustainable Chemistry

Jie Hu
Xian Hao Shan
Shan Wu
Peng Fei Sun
Zhengyuan Gao
Zhong Ren
Shuai Wang
Xiao Chao Feng

Frontiers in Chemistry

doi 10.3389/fchem.2025.1621188

226 views

Original Research

Published on 19 May 2025

Engineering of antimicrobial peptide Brevinin-1pl: arginine, lysine, and histidine substitutions enhance antimicrobial-anticancer efficacy with reduced cytotoxicity

in Medicinal and Pharmaceutical Chemistry

Jingkai Wang
Fanli Zeng
Xiaoling Chen
Tao Wang
Lei Wang
Mei Zhou
Yangyang Jiang
Tianbao Chen
Yongfei Fang
Jinwei Zhang

Frontiers in Chemistry

doi 10.3389/fchem.2025.1579097

741 views

Original Research

Published on 19 May 2025

GlycoIP: an integrated platform for simultaneous and site-specific N/O-glycosylation analysis of human semen

in Analytical Chemistry

Gaoshu Yan
Fei Cai
Keliang Wu
Qingyuan Cheng
Yong Zhang
Lin Fan

Frontiers in Chemistry

doi 10.3389/fchem.2025.1569561

516 views

Original Research

Published on 19 May 2025

H2 production in underground coal gasification with pretreatment by non-focusing microwave

in Green and Sustainable Chemistry

Lele Feng
Jie Dong
Haidong Li
Jiaxuan Sun

Frontiers in Chemistry

doi 10.3389/fchem.2025.1586267

348 views

Original Research

Published on 19 May 2025

Pore-scale numerical simulation of in situ microemulsion formation and enhanced oil recovery in porous media

in Green and Sustainable Chemistry

Yingxue Hu
Kai Dong
Dan Zhang
Tianjiang Wu
Wei Xu
Zhaolin Gu

Frontiers in Chemistry

doi 10.3389/fchem.2025.1601086

327 views

Original Research

Accepted on 16 May 2025

Vineyard pruning-wood waste valorisation: sustainable extraction of bioactive compounds

in Green and Sustainable Chemistry

Elisabetta Tumminelli
Valeria Cavalloro
Chiara Ingrà
Alessandra Ferrandino
Alessio Porta
Giorgio Marrubini
Emanuela Martino
Daniela Rossi
Simona Collina

Frontiers in Chemistry

doi 10.3389/fchem.2025.1597833

245 views

Original Research

Accepted on 15 May 2025

Hydrogen-Centric Machine Learning Approach for Analyzing Properties of Tricyclic Anti-depressant Drugs

in Theoretical and Computational Chemistry

Ravi Sankar J.
Simran Kour

Frontiers in Chemistry

doi 10.3389/fchem.2025.1603948

299 views