Frontiers in Immunology | NK and Innate Lymphoid Cell Biology

Review

Published on 21 Jul 2025

Unraveling NK cell heterogeneity through single-cell sequencing: insights from physiological and tumor contexts for clinical applications

in NK and Innate Lymphoid Cell Biology

Mingxin Shen
Yutong Liu
Liang Shao
Meng Qu
Shixin Song
Wei Sun
Hao Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1612352

Review

Accepted on 15 Jul 2025

Natural killer cells in skin: a unique opportunity to better characterize the many facets of an overlooked secondary lymphoid organ

in NK and Innate Lymphoid Cell Biology

Kirsten M Johnson
Dean Anthony Lee

Frontiers in Immunology

doi 10.3389/fimmu.2025.1646719

118 views

Review

Published on 11 Jul 2025

CAR-iNKT cells: redefining the frontiers of cellular immunotherapy

in NK and Innate Lymphoid Cell Biology

Magdalena Niedzielska
Amy Chalmers
Martyna C. Popis
Efrat Altman-Sharoni
Stephen Addis
Rebekka Beulen
Nils-Petter Rudqvist
Eleni Chantzoura
Marco A. Purbhoo
Dhan Chand

Frontiers in Immunology

doi 10.3389/fimmu.2025.1625426

1,428 views

Correction

Published on 04 Jul 2025

Correction: PM21-particle stimulation augmented with cytokines enhances NK cell expansion and confers memory-like characteristics with enhanced survival

in NK and Innate Lymphoid Cell Biology

Jeremiah L. Oyer
Tayler J. Croom-Perez
Md Faqrul Hasan
Javier A. Rivera-Huertas
Sarah B. Gitto
Joanna M. Mucha
Xiang Zhu
Deborah A. Altomare
Robert Y. Igarashi
Alicja J. Copik

Frontiers in Immunology

doi 10.3389/fimmu.2025.1650274

367 views

Mini Review

Published on 26 Jun 2025

Does a natural killer need a CAR?

in NK and Innate Lymphoid Cell Biology

Kangbo Wang
Yumo Zhang
Zhibo Han
Youwei Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1606126

1,582 views

Original Research

Accepted on 20 Jun 2025

RAG recombinase expression discriminates the development of natural killer cells

in NK and Innate Lymphoid Cell Biology

Jasmin Sprissler
Ulrich Pannicke
Eva-Maria Rump
Hubert Schrezenmeier
Nicolas Casadei
Michaela Pogoda
Laurence Kuhlburger
Morgana Barroso Oquendo
Stefan Czemmel
Klaus-Michael Debatin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1607664

263 views

Review

Published on 19 Jun 2025

Designs of NKG2D-based immunotherapeutics for cancer

in NK and Innate Lymphoid Cell Biology

Jianfeng Han
Youwei Wang
Godfrey Chi-Fung Chan
Wing Keung Chan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1557644

1,559 views

Original Research

Published on 16 Jun 2025

Transcriptomic and proteomic signatures of host NK cells delineate distinct immune states across tuberculosis infection statuses

in NK and Innate Lymphoid Cell Biology

Han Zhang
Liguo Liu
Jie Hu
Xiaolin Wu
Jianhua Zheng
Henan Xin
Jiang Du
Jiarong Yang
Zizheng Lv
Zhuoran Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1607770

1,233 views

Original Research

Published on 11 Jun 2025

Innate lymphoid cells in bone marrow and peripheral blood of healthy individuals and in bone marrow of patients with myelodysplastic syndromes

in NK and Innate Lymphoid Cell Biology

Laiz C. Bento
Guilherme Martelossi Cebinelli
Nydia Strachman Bacal
Luciana Cavalheiro Marti

Frontiers in Immunology

doi 10.3389/fimmu.2025.1568875

1,009 views

Original Research

Published on 04 Jun 2025

Impact of a moderate-intensity aerobic exercise intervention on systemic and uterine natural killer cells in women with unexplained recurrent pregnancy loss

in NK and Innate Lymphoid Cell Biology

Aysel Gurbanova
Amber E. M. Lombardi
Denise H. J. Habets
Salwan Al-Nasiry
Marc E. A. Spaanderman
Marien I. de Jonge
Tess Meuleman
Lotte Wieten
Renate G. van der Molen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1602939

2,117 views

Original Research

Accepted on 02 Jun 2025

Serum 17□□-estradiol inversely correlates with circulating group 2 innate lymphoid cells in a cohort of asthmatic patients

in NK and Innate Lymphoid Cell Biology

Elizabeth Myers
Samuel E. Aamodt
Tom P. Huecksteadt
Robert Paine
Mustafa Mir-Kasimov
Christopher Reilly
Sean J. Callahan
Karl Sanders
Kristi J. Warren

Frontiers in Immunology

doi 10.3389/fimmu.2025.1555228

176 views

Review

Published on 29 May 2025

Novel strategies to overcome tumor immunotherapy resistance using CAR NK cells

in NK and Innate Lymphoid Cell Biology

Jun-Hui Guo
Ali Afzal
Sadia Ahmad
Ghazala Saeed
Amna Rehman
Umair Ali Khan Saddozai
Lei Liu
Shi-Hao Guo
Xin-Ying Ji
Muhammad Babar Khawar

Frontiers in Immunology

doi 10.3389/fimmu.2025.1550652

1,887 views

Original Research

Published on 26 May 2025

Construction of stable packaging cell lines for large-scale industrial BaEV-enveloped retroviral vector production

in NK and Innate Lymphoid Cell Biology

Lijun Zhao
Chunting Qiu
Hanyi Chen
Zhuoying Yu
Jiaqi Fan
Qihong Ma
Sijian Zhan
Yaru Feng
Xiaorui Li
Ping Ma

Frontiers in Immunology

doi 10.3389/fimmu.2025.1578660

1,561 views

Review

Published on 23 May 2025

Application and prospects of genetic engineering in CAR-NK cell therapy

in NK and Innate Lymphoid Cell Biology

Caidong Hu
Wenhong Lai
Bin Tian
Xi Xu
Shuiling Xie
Wenting Zhong
Huiqiang Kang
Xiaoyun Chen
Hailiang Li
Jingxin Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1600411

1,809 views

Original Research

Published on 15 May 2025

Single cell atlas of canine natural killer cells identifies distinct circulating and tissue resident gene profiles

in NK and Innate Lymphoid Cell Biology

Aryana M. Razmara
Marshall Lammers
Sean J. Judge
William J. Murphy
Cameron E. Gaskill
William T.N. Culp
Alicia A. Gingrich
Zachary S. Morris
Robert B. Rebhun
C. Titus Brown

Frontiers in Immunology

doi 10.3389/fimmu.2025.1571085

1,766 views

Original Research

Published on 13 May 2025

Functional screening of somatic mutant events in extranodal natural killer/T-cell lymphoma with adrenal involvement

in NK and Innate Lymphoid Cell Biology

Luxin Zhang
Haifeng Gao
Shuang Ma
Xiaoming Fan
Huahang Guo
Man Sun
Shuang Wen
Tianqing Liu
Guanghai Yu
Xiaoying Yuan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1566794

1,660 views