Frontiers in Oncology

Case Report

Published on 05 Dec 2025

Long-term progression-free survival with first-line pyrotinib monotherapy in a treatment-naïve stage IV NSCLC patient harboring an ERBB2 exon 20 insertion: a case report

in Thoracic Oncology

Zhenyu Ke
Hongbo Yang
Meng Xing
Shasha Bi
Fujun Yang

Frontiers in Oncology

doi 10.3389/fonc.2025.1637973

465 views

Case Report

Published on 05 Dec 2025

Case report: TP53 heterogeneous alteration in grade 3 type I gastric NET: a case implicating primary tumor progression

in Cancer Molecular Targets and Therapeutics

Yan Li
Yuekui Bai
Hongjuan Ti
Chunyu Zhou
Qian Liu
Ying Dong

Frontiers in Oncology

doi 10.3389/fonc.2025.1708609

502 views

Original Research

Published on 05 Dec 2025

Multiparametric quantitative MRI combining SyMRI and MUSE-DWI for noninvasive stratification of HER2 status in breast cancer

in Cancer Imaging and Image-directed Interventions

Kui Yang
Wei Zhang
Hao Zheng
Da Shuang Ji
Hu Chang
Feng Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1709170

513 views

Review

Published on 05 Dec 2025

CD39+PD-1+ regulatory T cells in melanoma: key drivers of systemic immunosuppression and prognostic biomarkers

in Cancer Immunity and Immunotherapy

Guanlin Qiao
Hongxia He
Xiaobing Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1724062

491 views

Mini Review

Published on 05 Dec 2025

Prognostic biomarkers in oral squamous cell carcinoma: current evidence and future directions

in Head and Neck Cancer

Phillipp Brockmeyer

Frontiers in Oncology

doi 10.3389/fonc.2025.1692294

512 views

Original Research

Published on 05 Dec 2025

Computed tomography features and clinicopathological characteristics of resectable esophageal sarcomatoid carcinoma: a retrospective study

in Cancer Imaging and Image-directed Interventions

Meng Li
Yang Li
Mingbo Wang
Huiyan Deng
Xiangming Wang
Gaofeng Shi
Andu Zhang
Jialiang Ren

Frontiers in Oncology

doi 10.3389/fonc.2025.1655957

348 views

Original Research

Published on 05 Dec 2025

Investigating object detection errors in endoscopic imaging of esophageal SCC and dysplasia through precision–recall analysis

in Cancer Imaging and Image-directed Interventions

Li-Jen Chang
Kun-Hua Lee
Arvind Mukundan
Riya Karmakar
Achmad Bauravindah
Tsung-Hsien Chen
Chien-Wei Huang
Hsiang-Chen Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1707854

436 views

Original Research

Published on 05 Dec 2025

Patterns of care in pancreatic cancer radiotherapy: impact of facility volume on outcomes

in Radiation Oncology

Arvind Rajan
Elizabeth M. Gleeson
Veronica Pham
Karyn A. Goodman

Frontiers in Oncology

doi 10.3389/fonc.2025.1654223

416 views

Case Report

Published on 05 Dec 2025

Case Report: Popliteal arterial tumor embolus as the initial presentation of EGFR-mutant lung adenocarcinoma with pulmonary-vein invasion

in Thoracic Oncology

Yongchun Hong
Xinjing Ding
Jianghua Ding

Frontiers in Oncology

doi 10.3389/fonc.2025.1731314

313 views

Original Research

Published on 05 Dec 2025

Emodin inhibits colon cancer tumor growth by suppressing tumor cell glycolysis through inhibition of NAT10-mediated PGK1 ac4C modification

in Gastrointestinal Cancers: Colorectal Cancer

Zhuoxin Wei
Zhuo Lv
Weimin Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1575391

541 views

Case Report

Published on 05 Dec 2025

Eribulin and sintilimab combined with radiotherapy in a heavily pretreated patient with advanced retroperitoneal myxoid pleomorphic liposarcoma: a case report and literature review

in Cancer Immunity and Immunotherapy

Hongyu Zhuo
Dongna Li
Yang Fu
Xinyao Zhang
Xin He
Ying Xu
Jie Liu
Yu Jiang
Yaotiao Deng

Frontiers in Oncology

doi 10.3389/fonc.2025.1719603

384 views

Opinion

Published on 05 Dec 2025

Commentary: Clinical efficacy of plasmid encoding p62/SQSTM1 (Elenagen) in combination with gemcitabine in patients with platinum-resistant ovarian cancer: a randomized controlled trial

in Gynecological Oncology

Shuyan Li
Guanze Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1727892

381 views

Hypothesis and Theory

Published on 05 Dec 2025

Spatially optimized 125I brachytherapy: a novel immunomodulatory approach based on spatially fractionated radiation therapy principles

in Radiation Oncology

Qiyu Sun
Yanbo Hu
Zhiqian Sun
Lulu Du
Rui Huang
Lichao Wang
Zhenzhen Cui
Jiaxin Yang
Xiaowen Ma
Min Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1693574

418 views

Original Research

Accepted on 04 Dec 2025

Differential Diagnosis of Benign and Malignant Vertebral Compression Fractures Based on CT Radiomics Model

in Cancer Imaging and Image-directed Interventions

Xinrui Liu
Song Chen
Yifan Wang
Jiashi Cao
Zhuangfei Niu
Yuxian Jin
Xingdan Pan
Zhengwei Zhang
Tielong Liu
Wei Liang

Frontiers in Oncology

Original Research

Accepted on 04 Dec 2025

Identification of Endogenous Reference Genes for RT-qPCR Analysis in Breast Cancer and Matched Adjacent Tissues

in Breast Cancer

Kai Zhang
Yue Meng
Ya-Wen Wang
Zhi-Bao Xu
Zhong-Qi Qiao
Can Liu
Yan-Duo Chen
Yao Xu

Frontiers in Oncology

158 views

Original Research

Accepted on 04 Dec 2025

Interleukin 1 family dysregulation in serum and peritoneal fluid of ovarian cancer patients – potential clinical implications

in Gynecological Oncology

Sebastian Stępień
Marta Smycz - Kubańska
Maria-Laura Morawiec
Kamil Radosław Seweryn
Aleksandra Mielczarek-Palacz

Frontiers in Oncology

172 views

Case Report

Accepted on 04 Dec 2025

Management of Malignant Breast Phyllodes Tumor with Rib Invasion during Pregnancy: A Case-Based Review

in Breast Cancer

Panni Li
Wenwen Wu
Xianan Guo
Huihui Chen
Kexin Liu
Dan Ye
Zhihua Teng
Wei He
Liquan Wang
Yunxiang Zhou

Frontiers in Oncology

156 views

Original Research

Accepted on 04 Dec 2025

Ensemble learning for predicting microsatellite instability in colorectal cancer using pretreatment colonoscopy images and clinical data

in Gastrointestinal Cancers: Colorectal Cancer

Jia You
Shenghan Zhang
Jianjie Zhang
Yaru Chen
Mengmeng Zhang
Chungen Zhou
Bin Jiang

Frontiers in Oncology

112 views

Original Research

Accepted on 04 Dec 2025

Vaginal lavage fluid can serve as a reliable method for early screening of endometrial cancer: a proof-of-concept study

in Gynecological Oncology

Yibing Li
Ping Ren
Jiazhen Huang
Shuang Tan
Ning Wang

Frontiers in Oncology

141 views

Review

Accepted on 04 Dec 2025

Engineering the Next Generation of CAR T-Cells: Precision Modifications, Logic Gates and Universal Strategies to Overcome Exhaustion and Tumor Resistance

in Cancer Immunity and Immunotherapy

Juan Esteban Garcia-Robledo
Sergio Cabrera-Salcedo
Andreas Michael Brandauer
Francesco Romano
Joshua Rengifo-Martinez
Alejandro Toro-Pedroza
Juan Sebastián Victoria
Lady Johana Rios
Alexandre Loukanov
Andrés Felipe Cardona

Frontiers in Oncology

124 views

Review

Accepted on 04 Dec 2025

Meta-analysis of the Efficacy and Safety of Kanglaite Injection in Conjunction with Chemotherapy for Cancer Pain

in Cancer Epidemiology and Prevention

Gaofei Feng
Shujing Yi
Ruo Chen
Peng Liu
Yuanqi Li
Yuantao Zhong
Zhaowen Peng
Yufei Liu
Shu Xu

Frontiers in Oncology

126 views

Case Report

Published on 04 Dec 2025

Synchronous angiomyolipoma with epithelial cysts and clear cell renal cell carcinoma: a case report

in Genitourinary Oncology

Jian Wang
Chengde Ren
Ziyang Qiang
Jintao Li
Hailin Ren
Guojun Chen
Xue Gong
Jiaxin Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1618337

515 views

Original Research

Published on 04 Dec 2025

Cervical cancer classification using a novel hybrid approach

in Cancer Imaging and Image-directed Interventions

Jheelam Mondal
Rajdeep Chatterjee
Mahendra Kumar Gourisaria
Manoj Sahni
Ernesto León-Castro

Frontiers in Oncology

doi 10.3389/fonc.2025.1703772

699 views

Systematic Review

Published on 04 Dec 2025

Systematic review of artificial intelligence and radiomics for preoperative prediction of extranodal extension and lymph node metastasis in oropharyngeal cancer

in Head and Neck Cancer

Katarzyna Stawarz
Anna Gorzelnik
Wojciech Klos
Jacek Korzon
Filip Kissin
Karolina Bieńkowska-Pluta
Grzegorz Stawarz
Natalia Rusetska
Jakub Zwolinski

Frontiers in Oncology

doi 10.3389/fonc.2025.1717641

463 views

34,173 articles

articles

Long-term progression-free survival with first-line pyrotinib monotherapy in a treatment-naïve stage IV NSCLC patient harboring an ERBB2 exon 20 insertion: a case report

Case report: TP53 heterogeneous alteration in grade 3 type I gastric NET: a case implicating primary tumor progression

Multiparametric quantitative MRI combining SyMRI and MUSE-DWI for noninvasive stratification of HER2 status in breast cancer

CD39+PD-1+ regulatory T cells in melanoma: key drivers of systemic immunosuppression and prognostic biomarkers

Prognostic biomarkers in oral squamous cell carcinoma: current evidence and future directions

Computed tomography features and clinicopathological characteristics of resectable esophageal sarcomatoid carcinoma: a retrospective study

Investigating object detection errors in endoscopic imaging of esophageal SCC and dysplasia through precision–recall analysis

Patterns of care in pancreatic cancer radiotherapy: impact of facility volume on outcomes

Case Report: Popliteal arterial tumor embolus as the initial presentation of EGFR-mutant lung adenocarcinoma with pulmonary-vein invasion

Emodin inhibits colon cancer tumor growth by suppressing tumor cell glycolysis through inhibition of NAT10-mediated PGK1 ac4C modification

Eribulin and sintilimab combined with radiotherapy in a heavily pretreated patient with advanced retroperitoneal myxoid pleomorphic liposarcoma: a case report and literature review

Commentary: Clinical efficacy of plasmid encoding p62/SQSTM1 (Elenagen) in combination with gemcitabine in patients with platinum-resistant ovarian cancer: a randomized controlled trial

Spatially optimized 125I brachytherapy: a novel immunomodulatory approach based on spatially fractionated radiation therapy principles

Differential Diagnosis of Benign and Malignant Vertebral Compression Fractures Based on CT Radiomics Model

Identification of Endogenous Reference Genes for RT-qPCR Analysis in Breast Cancer and Matched Adjacent Tissues

Interleukin 1 family dysregulation in serum and peritoneal fluid of ovarian cancer patients – potential clinical implications

Management of Malignant Breast Phyllodes Tumor with Rib Invasion during Pregnancy: A Case-Based Review

Ensemble learning for predicting microsatellite instability in colorectal cancer using pretreatment colonoscopy images and clinical data

Vaginal lavage fluid can serve as a reliable method for early screening of endometrial cancer: a proof-of-concept study

Engineering the Next Generation of CAR T-Cells: Precision Modifications, Logic Gates and Universal Strategies to Overcome Exhaustion and Tumor Resistance

Meta-analysis of the Efficacy and Safety of Kanglaite Injection in Conjunction with Chemotherapy for Cancer Pain

Synchronous angiomyolipoma with epithelial cysts and clear cell renal cell carcinoma: a case report

Cervical cancer classification using a novel hybrid approach

Systematic review of artificial intelligence and radiomics for preoperative prediction of extranodal extension and lymph node metastasis in oropharyngeal cancer