REVIEW article
Front. Plant Sci.
Sec. Plant Systematics and Evolution
Volume 16 - 2025 | doi: 10.3389/fpls.2025.1586624
Morphological, molecular, and pharmacological review of Veldt Grape (Cissus quadrangularis L.): An underutilized medicinal plant
Provisionally accepted
- VIT University, Vellore, India
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Cissus quadrangularis, commonly known as veldt grape, is an underutilized medicinal plant belonging to the Vitaceae family, widely found in tropical regions of India with diverse populations. The plant is also known for its rich phytochemical profile, including ketosteroids and flavonoids that enhance osteoblast activity and accelerate fracture healing. Also, this genus is unique in having a high degree of drought tolerance due to its facultative Crassulacean Acid Metabolism (CAM) pathway. The CAM pathway in C. quadrangularis enhances its ability to sustain metabolic activity under drought stress, contributing to its survival and medicinal value in resource-limited ecosystems. The genetic variability among various veldt grape ecotypes plays a crucial role in determining the concentration of bioactive compounds and other physiological traits. This review aims to understand the relationship through morphological and molecular aspects of this plant and its application in pharmacology, with other potential therapeutic applications. C. quadrangularis, being an under-utilized medicinal crop with enormous pharmaceutical significance, lacks knowledge of its genetic wealth poses a major barrier to commercial cultivation all over India. Hence, the morphological and molecular markers are a perfect approach to conserving this valuable plant's genetic resources and crop improvement.
Keywords: Veldt grape, osteoblast activity, CAM pathway, morphological, molecular
Received: 03 Mar 2025; Accepted: 12 May 2025.
Copyright: © 2025 K and Kumar. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: S.Ramesh Kumar, VIT University, Vellore, India
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