REVIEW article
Front. Plant Sci.
Sec. Plant Cell Biology
Volume 16 - 2025 | doi: 10.3389/fpls.2025.1599323
This article is part of the Research TopicENPER2024 - Three Decades of Endomembrane ResearchView all articles
The clues offered by SNAREs on the vacuoles of plants and animals
Provisionally accepted
- 1Di.S.Te.B.A (Dipartimento di Scienze e Tecnologie Biologiche ed Ambientali), University of Salento, Lecce, Italy
- 2GreenUPorto – Sustainable Agrifood Production Research Centre and INOV4AGRO , Faculty of Sciences of University of Porto, Porto, Portugal
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Vacuoles and Lysosome Related Organelles (LROs) are essential compartments in eukaryotic cells, playing crucial roles in storage, degradation, signaling, and homeostasis. Despite their functional similarities, these organelles have traditionally been studied in isolation within plant and animal cell biology. This review bridges these disciplines by exploring the molecular parallels between plant vacuoles and animal LROs, with a particular emphasis on the SNARE (Soluble N-ethylmaleimidesensitive factor Attachment Protein Receptor) protein family, which governs membrane fusion and trafficking. SNARE complexes orchestrate intracellular transport, ensuring the correct delivery of cargo to vacuoles and LROs. By analyzing SNARE homologs and their interactions across kingdoms, we highlight conserved mechanisms that regulate organelle biogenesis, remodeling, and function. This comparative approach not only advances our understanding of cellular compartmentalization but also sheds light on potential applications in biotechnology, stress adaptation, and human disease research. Integrating knowledge from plant and animal systems offers a powerful framework for discovering novel regulatory pathways in membrane trafficking and cellular homeostasis.
Keywords: Vacuoles, LROs, Melanocytes, Adipocytes, lipid droplets, SNAREs
Received: 24 Mar 2025; Accepted: 19 May 2025.
Copyright: © 2025 Barozzi, Sampaio, Pereira and Di Sansebastiano. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Cláudia Pereira, GreenUPorto – Sustainable Agrifood Production Research Centre and INOV4AGRO , Faculty of Sciences of University of Porto, Porto, Portugal
Gian Pietro Di Sansebastiano, Di.S.Te.B.A (Dipartimento di Scienze e Tecnologie Biologiche ed Ambientali), University of Salento, Lecce, 73100, Italy
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.