ORIGINAL RESEARCH article
Front. Plant Sci.
Sec. Plant Metabolism and Chemodiversity
Volume 16 - 2025 | doi: 10.3389/fpls.2025.1617634
Comparative metabolomic profiling of Lupinus albus and L. angustifolius harvest residues: Exploring chemical diversity and valorization potential
Provisionally accepted
- 1Environmental Research and Innovation (ERIN), Luxembourg Institute of Science and Technology (LIST), Esch-sur-Alzette, Luxembourg
- 2Résistance Induite et Bioprotection des Plantes, Université de Reims Champagne-Ardenne, Reims, Champagne-Ardenne, France
- 3Institut fir Biologesch Landwirtschaft an Agrarökologie Luxemburg a.s.b.l (IBLA), 1 Wantergaass,L-7664 Medernach, Luxembourg
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Lupin species are a rich source of bioactive compounds with diverse industrial applications, yet their harvest residues remain underutilized. This study investigates the metabolomic composition of the harvest residues of different Lupinus albus and L. angustifolius varieties to explore species-specific biochemical differences and valorization potential.Methanolic extracts from the harvest residues were analyzed using UHPLC-MS/MS, leading to the tentative identification of 181 compounds, with saponins and flavonoids identified as the predominant metabolite classes.The data reveal distinct metabolic profiles: L. albus is characterized by higher levels of isoflavonoids (luteone), flavonols (isorhamnetin), and flavanones (naringenin), which were detected as free aglycones, glycosylated derivatives, and, for some compounds, as malonylated glycosides, which correlate with a higher antioxidant capacity. In contrast, extracts from L. angustifolius contain higher amounts of saponins, particularly soyasaponins B, E, A, and DDMP, as well as flavones (chrysoeriol and derivatives) and isoflavones (genistein and wighteone and its derivatives). Correlation analysis confirmed that a positive relationship exists between flavonoids and antioxidant activity, while saponins showed a negative correlation with antioxidant potential. This study highlights the distinct valorization opportunities of Lupinus residues: L. albus, rich in antioxidants and defence-related metabolites, holds promise for nutraceutical, pharmaceutical, and functional food applications as well as plant protection strategies. In contrast, L. angustifolius, with its high saponin content, has potential for biopesticides and antimicrobial agents. This study underscores the sustainability potential of Lupinus harvest residues as a renewable resource, supporting the upcycling of agricultural byproducts into high-value bioactive products.
Keywords: L. albus, L. angustifolius, Harvest residues, Saponins, Flavonoids, Valorization
Received: 25 Apr 2025; Accepted: 14 Jun 2025.
Copyright: © 2025 Halime, Renaut, Zimmer, Heidt, Jacquard and Sergeant. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Kjell Sergeant, Environmental Research and Innovation (ERIN), Luxembourg Institute of Science and Technology (LIST), Esch-sur-Alzette, 4422, Luxembourg
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.