ORIGINAL RESEARCH article
Front. Plant Sci.
Sec. Plant Bioinformatics
Volume 16 - 2025 | doi: 10.3389/fpls.2025.1652613
This article is part of the Research TopicBioinformatics and Beyond: Exploring the Health Benefits of Bioactive Metabolites from PlantsView all 3 articles
Genome-Wide identification of the COBRA-Like Gene Family and expression pattern analysis under abiotic stresses of Sorghum bicolor (L.)
Provisionally accepted
Shipeng Liu*Jingtin Rui
Shuang LiangHairuo WangXinyi GuoQuan MaJunshen Wang
Kai Wang*Xiaolong HeHaibing ZhaoWenting JiangXiangqian Zhang- Yan'an University School of Life Science, Yan'an, China
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COBRA-Like (CBL) genes encode glycosylphosphatidylinositol (GPI) -anchored proteins specific to plants that play important roles in cellulose biosynthesis in primary and secondary cell walls. This study used a bioinformatics approach to characterize the CBL family genes in Sorghum bicolor (S. bicolor) at the genome-wide level to investigate their potential functions in S. bicolor development. The results revealed the identification of 10 CBL genes in the BTx623 and E048 S. bicolor genomes, respectively. A comparative analysis of conserved Motifs revealed that all CBL family genes in S. bicolor possess CCVS conserved structural domains. Phylogenetic analysis revealed that the family can be divided into two subfamilies, with genes within each subfamily exhibiting similar gene structures and physicochemical properties. Whole Genome Duplication (WGD) played an important role in the expansion of SbCBL gene family. The tissue-specific expression patterns of SbCBL genes suggest varying expression levels across different organs and tissues in S. bicolor, with SbCBL1, SbCBL5, and SbCBL9 showing significantly higher expression levels in roots. PEG and NaCl treatments significantly affected SbCBL expression levels. SbCBL4 expression increased after PEG treatment, while SbCBL9 expression decreased after NaCl treatment. Overall, this study provides new insights into the role of the CBL gene family in S. bicolor.
Keywords: SbCBL gene family, Systematic evolution, Whole genome duplication, abiotic stresses, SbCBL4/9
Received: 24 Jun 2025; Accepted: 19 Aug 2025.
Copyright: © 2025 Liu, Rui, Liang, Wang, Guo, Ma, Wang, Wang, He, Zhao, Jiang and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Shipeng Liu, Yan'an University School of Life Science, Yan'an, China
Kai Wang, Yan'an University School of Life Science, Yan'an, China
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