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REVIEW article

Front. Plant Sci.

Sec. Plant Nutrition

From Soil to Nutrition: Integrating Molecular Mechanisms and Agronomic Strategies for Selenium Biofortification in Horticultural Crops

Provisionally accepted
Lixia  WangLixia Wang1Fahad  ShafiqFahad Shafiq2Zheli  DingZheli Ding1Yingdui  HeYingdui He1*
  • 1National Key Laboratory for Tropical Crop Breeding, Institute of Tropical Bioscience and Biotechnology, Sanya Research Institute, Chinese Academy of Tropical Agricultural Sciences, Sanya, China
  • 2Government College University Lahore, Lahore, Pakistan

The final, formatted version of the article will be published soon.

Selenium (Se) is an essential element for humans. Biologically, it is incorporated into selenoproteins, which play crucial roles in thyroid hormone metabolism, immune system regulation, and antioxidant capacity. However, Se deficiency is a global health concern, affecting over 1 billion individuals, and the production of Se-fortified crops is inevitable. As a way forward, the biofortification of horticultural crops could improve Se nutrition. For plants, Se is a beneficial element, and crops exhibit significant variation in their ability to uptake Se which is also influenced by soil pH. Therefore, this review focuses on recent advancements in Se biofortification technologies for horticultural crops, including soil and foliar application methods, and explores the physiological processes and genetic mechanisms underlying Se uptake, transport, and assimilation in these crops. Furthermore, the effectiveness of different Se-salts in the regulation of Se levels in crops has been discussed, with special emphasis on the mechanisms involved.

Keywords: biofortification, Human Nutrition, Horticultural crops, Selenium, Selenoproteins

Received: 28 Sep 2025; Accepted: 11 Nov 2025.

Copyright: © 2025 Wang, Shafiq, Ding and He. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Yingdui He, yfzhglyjz@163.com

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