
Frontiers news
26 Jun 2023
Designer phages: World Economic Forum emerging technologies report
As a World Economic Forum platform partner, Frontiers is collaborating with the Forum on the 2023 edition of its annual emerging technologies report. Chosen by an international panel of experts, the list of top ten emerging technologies included in the report were selected from nearly 100 contenders based on criteria including novelty, applicability, depth, and power. Credit: Frontiers Designer phages There has been a growing recognition of the crucial role in human health played by the microbiome—the community of microbes living on and within the body. Recent advances in synthetic biology have allowed the engineering of the microbiome using phages – viruses that selectively infect specific types of bacteria. This creation of so-called designer phages has been identified by the Forum as one of this year’s top ten emerging technologies. By reprogramming phages using laboratory tools, individual bacterial species can be targeted to produce therapeutic molecules or to become sensitive to specific drugs. Mine Orlu of the steering committee for the Forum report stated: “Engineering microbiomes using designer phages represents a groundbreaking approach to improving human well-being and agricultural productivity. By reprogramming the genetic information of these viruses, scientists can selectively target specific bacteria to prevent or treat diseases in […]