Frontiers in Cell and Developmental Biology | Molecular and Cellular Pathology

Original Research

Published on 06 Mar 2025

Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model

in Molecular and Cellular Pathology

Wenyu Zhuo
Mingyang Zhang
Jiajia Tan
Yang Gao
Yan Wang
Nana Wang
Jin Ma
Jiaying Zhang
Zhiheng Liu
Haitao Lv

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1550220

4,829 views

Original Research

Published on 06 Mar 2025

Combining TNF-α silencing with Wnt3a overexpression: a promising gene therapy for particle-induced periprosthetic osteolysis

in Molecular and Cellular Pathology

Ping Chen
Long Wu
Shuai Zhang
Qunhua Jin
Kening Sun

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1511577

1,816 views

Review

Published on 05 Mar 2025

Research progress on small extracellular vesicles in diabetic nephropathy

in Molecular and Cellular Pathology

Bingqing Yu
Lanfeng Wang
Yiping Mao
Xinyi Hu
Yukang Lu
Jiahui He
Xiaoying Yuan
Man Zhang
Zhiping Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1535249

3,031 views

Original Research

Published on 05 Mar 2025

New evidence for T-cadherin in COVID-19 pathogenesis, endothelial dysfunction, and lung fibrosis

in Molecular and Cellular Pathology

Ekaterina Semina
Vladimir Popov
Nikita Khabibullin
Polina Klimovich
Veronika Sysoeva
Ella Kurilina
Zoya Tsokolaeva
Vsevolod Tkachuk
Kseniya Rubina

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1476329

2,682 views

Original Research

Published on 28 Feb 2025

Evaluating oxidative stress targeting treatments in in vitro models of placental stress relevant to preeclampsia

in Molecular and Cellular Pathology

Dinara Afrose
Matt D. Johansen
Valentina Nikolic
Natasa Karadzov Orlic
Zeljko Mikovic
Milan Stefanovic
Zoran Cakic
Philip M. Hansbro
Lana McClements

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1539496

4,161 views
7 citations

Original Research

Published on 27 Feb 2025

Filtered and unfiltered lipoaspirates reveal novel molecular insights and therapeutic potential for osteoarthritis treatment: a preclinical in vitro study

in Molecular and Cellular Pathology

Alissa Behn
Saskia Brendle
Marianne Ehrnsperger
Magdalena Zborilova
Thomas M. Grupp
Joachim Grifka
Nicole Schäfer
Susanne Grässel

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1534281

2,644 views

Review

Published on 26 Feb 2025

Harnessing exercise to combat chronic diseases: the role of Drp1-Mediated mitochondrial fission

in Molecular and Cellular Pathology

Yingxin Sun
Junchen He
Lei Bao
Xiaoming Shi
Jinghong Wang
Qingwen Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1481756

5,297 views
4 citations

Review

Published on 24 Feb 2025

Autophagy: regulating the seesaw of bone–fat balance

in Molecular and Cellular Pathology

Boya Zhang
Jing Cui
Xu Zhang
Ziyi Pan
Liuyi Du
RongRong Ye
Linlin Wen
Wenhao Zhai
Lei Huang
Daowei Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1465092

3,574 views
3 citations

Original Research

Published on 14 Feb 2025

Specific gut microbiota and serum metabolite changes in patients with osteoarthritis

in Molecular and Cellular Pathology

Wendong Wang
Xincheng Liu
Hao Nan
Huan Li
Litao Yan

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1543510

3,017 views
3 citations

Review

Published on 13 Feb 2025

Regulation of VEGFR3 signaling in lymphatic endothelial cells

in Molecular and Cellular Pathology

Kevin G. Kuonqui
Adana-Christine Campbell
Bracha L. Pollack
Jinyeon Shin
Ananta Sarker
Stav Brown
Hyeung Ju Park
Babak J. Mehrara
Raghu P. Kataru

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1527971

6,418 views
4 citations

Review

Published on 07 Feb 2025

Secondary prevention of preeclampsia

in Molecular and Cellular Pathology

Muhammad Ilham Aldika Akbar
Roudhona Rosaudyn
Khanisyah Erza Gumilar
Renuka Shanmugalingam
Gustaaf Dekker

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1520218

8,203 views
6 citations

Original Research

Published on 03 Feb 2025

Comparative analysis of retinal vascular structural parameters in populations with different glucose metabolism status based on color fundus photography and artificial intelligence

in Molecular and Cellular Pathology

Naimei Chen
Zhentao Zhu
Di Gong
Xinrong Xu
Xinya Hu
Weihua Yang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1550176

2,380 views
1 citation

Editorial

Published on 29 Jan 2025

Editorial: Vascular- and immuno-metabolism as drivers of cardiovascular disease: insights obtained from omics approaches

in Molecular and Cellular Pathology

Emiel P. C. van der Vorst
Jeffrey Kroon
Raquel Guillamat-Prats
Yvonne Döring

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1559828

1,806 views

Original Research

Published on 28 Jan 2025

Blinking characteristics analyzed by a deep learning model and the relationship with tear film stability in children with long-term use of orthokeratology

in Molecular and Cellular Pathology

Yue Wu
Siyuan Wu
Yinghai Yu
Xiaojun Hu
Ting Zhao
Yan Jiang
Bilian Ke

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2024.1517240

3,574 views
3 citations

Original Research

Published on 28 Jan 2025

A novel multi-scale and fine-grained network for large choroidal vessels segmentation in OCT

in Molecular and Cellular Pathology

Wei Huang
Qifeng Yan
Lei Mou
Yitian Zhao
Wei Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1508358

1,617 views

Editorial

Published on 24 Jan 2025

Editorial: Advancements in proteomics and PTMomics: unveiling mechanistic insights and targeted therapies for metabolic diseases

in Molecular and Cellular Pathology

Xiulan Chen
Yanchang Li
Daniela Braconi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1556129

1,548 views
1 citation

Original Research

Published on 24 Jan 2025

MLL4 regulates postnatal palate growth and midpalatal suture development

in Molecular and Cellular Pathology

Jung-Mi Lee
Hunmin Jung
Bruno de Paula Machado Pasqua
Yungki Park
Qinghuang Tang
Shin Jeon
Soo-Kyung Lee
Jae W. Lee
Hyuk-Jae Edward Kwon

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1466948

3,101 views
3 citations

Brief Research Report

Published on 23 Jan 2025

The differentiation state of small intestinal organoid models influences prediction of drug-induced toxicity

in Molecular and Cellular Pathology

Jessica A. Klein
Julia D. Heidmann
Tomomi Kiyota
Aaron Fullerton
Kimberly A. Homan
Julia Y. Co

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1508820

6,015 views
3 citations

Original Research

Published on 22 Jan 2025

Hydroxyurea mitigates diabetic kidney disease through mTOR-S6K signaling pathway in STZ-induced diabetic mice

in Molecular and Cellular Pathology

Wanying Cheng
Cenzhu Wang
Meican Ma
Yu Zhou

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1529901

2,123 views
2 citations

Original Research

Published on 20 Jan 2025

The critical role of MLKL in hemorrhagic stroke and the therapeutic potential of its associated protein network

in Molecular and Cellular Pathology

Yi Wang
Moran Xu
Xiaoli Zuo
Sheng Wang
Yong Yu
Zhaobing Gao
Jingbo Qie
Ye Jiang
Fang Huang
Bingqing Xia

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2024.1509877

2,487 views
1 citation

Original Research

Published on 09 Jan 2025

Color fundus photograph-based diabetic retinopathy grading via label relaxed collaborative learning on deep features and radiomics features

in Molecular and Cellular Pathology

Chao Zhang
Guanglei Sheng
Jie Su
Lian Duan

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2024.1513971

1,932 views
2 citations

Original Research

Published on 08 Jan 2025

A multi-modal multi-branch framework for retinal vessel segmentation using ultra-widefield fundus photographs

in Molecular and Cellular Pathology

Qihang Xie
Xuefei Li
Yuanyuan Li
Jiayi Lu
Shaodong Ma
Yitian Zhao
Jiong Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2024.1532228

2,576 views
1 citation

Original Research

Published on 08 Jan 2025

Exploring the effect of gestational diabetes mellitus on retinal vascular morphology by PKSEA-Net

in Molecular and Cellular Pathology

Ligang Jiang
Yimei Ji
Mengting Liu
Ruolin Fang
Zhentao Zhu
Meizhen Zhang
Yuhua Tong

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2024.1532939

2,885 views
2 citations

Original Research

Published on 06 Jan 2025

Altered cytoskeleton dynamics in patient-derived iPSC-based model of PCDH19 clustering epilepsy

in Molecular and Cellular Pathology

Rossella Borghi
Stefania Petrini
Valentina Apollonio
Marina Trivisano
Nicola Specchio
Sandra Moreno
Enrico Bertini
Marco Tartaglia
Claudia Compagnucci

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2024.1518533

2,800 views
2 citations

2,452 articles

articles

Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model

Combining TNF-α silencing with Wnt3a overexpression: a promising gene therapy for particle-induced periprosthetic osteolysis

Research progress on small extracellular vesicles in diabetic nephropathy

New evidence for T-cadherin in COVID-19 pathogenesis, endothelial dysfunction, and lung fibrosis

Evaluating oxidative stress targeting treatments in in vitro models of placental stress relevant to preeclampsia

Filtered and unfiltered lipoaspirates reveal novel molecular insights and therapeutic potential for osteoarthritis treatment: a preclinical in vitro study

Harnessing exercise to combat chronic diseases: the role of Drp1-Mediated mitochondrial fission

Autophagy: regulating the seesaw of bone–fat balance

Specific gut microbiota and serum metabolite changes in patients with osteoarthritis

Regulation of VEGFR3 signaling in lymphatic endothelial cells

Secondary prevention of preeclampsia

Comparative analysis of retinal vascular structural parameters in populations with different glucose metabolism status based on color fundus photography and artificial intelligence

Editorial: Vascular- and immuno-metabolism as drivers of cardiovascular disease: insights obtained from omics approaches

Blinking characteristics analyzed by a deep learning model and the relationship with tear film stability in children with long-term use of orthokeratology

A novel multi-scale and fine-grained network for large choroidal vessels segmentation in OCT

Editorial: Advancements in proteomics and PTMomics: unveiling mechanistic insights and targeted therapies for metabolic diseases

MLL4 regulates postnatal palate growth and midpalatal suture development

The differentiation state of small intestinal organoid models influences prediction of drug-induced toxicity

Hydroxyurea mitigates diabetic kidney disease through mTOR-S6K signaling pathway in STZ-induced diabetic mice

The critical role of MLKL in hemorrhagic stroke and the therapeutic potential of its associated protein network

Color fundus photograph-based diabetic retinopathy grading via label relaxed collaborative learning on deep features and radiomics features

A multi-modal multi-branch framework for retinal vessel segmentation using ultra-widefield fundus photographs

Exploring the effect of gestational diabetes mellitus on retinal vascular morphology by PKSEA-Net

Altered cytoskeleton dynamics in patient-derived iPSC-based model of PCDH19 clustering epilepsy