Frontiers in Chemistry | Organic Chemistry

Original Research

Published on 05 Feb 2026

GO/MNPs–TEA–CuI in water: a green and efficient catalytic system for multicomponent preparation of highly substituted imidazoles and oxazoles

in Organic Chemistry

Mohamed Abu Shuheil
Ahmed Aldulaimi
Rekha M. M.
Subhashree Ray
Omayma Salim Waleed
C. P. Surya
Renu Sharma
Vatsal Jain

Frontiers in Chemistry

doi 10.3389/fchem.2025.1732911

405 views

Original Research

Published on 04 Feb 2026

Selective isomerization of 2,3-disubstituted butanediacetal esters and thioesters using lithium and sodium enolates: effects of bases and additives on stereoselectivity

in Organic Chemistry

Adam Drop
Magdalena Grzegolec
Bożena Frąckowiak-Wojtasek

Frontiers in Chemistry

doi 10.3389/fchem.2026.1750600

481 views

Original Research

Published on 30 Jan 2026

Synthesis, characterization and surface properties of an organosilicon surfactant

in Organic Chemistry

Xinhua Zhu
Yanyu Wang
He Huang
Yuqiang Zhang
Xuhong Jia
Maoyong Zhi

Frontiers in Chemistry

doi 10.3389/fchem.2026.1744604

572 views

Original Research

Accepted on 19 Jan 2026

Formation and Transfer Patterns of Key Aroma Compounds in Cigar Tobacco Based on SBSE-GC-O-MS, Pyrolysis-GC-O-MS and Flue Gas Analysis Correlation Studies

in Organic Chemistry

Xue Wu
Tianze Liu
Xu Wang
Chao Wang
Wentao Zhao
Yuqing Dou

Frontiers in Chemistry

161 views

Original Research

Published on 29 Dec 2025

Regioselective synthesis of novel spiro-isoxazolines congeners as antimicrobial agents: in vitro and in-silico assessments

in Organic Chemistry

Rachid Bouzammit
Soumia Ait Assou
Mohammed Er-Rajy
Noura Aflak
Lahoucine Bahsis
Mohammed Chalkha
Mohammed El Hassouni
Mohammed Lachkar
Taibi Ben Hadda
Daryn Benson

Frontiers in Chemistry

doi 10.3389/fchem.2025.1740409

1,326 views

Original Research

Published on 10 Dec 2025

Ultrasonic-assisted, additive-free Pd-catalyzed Suzuki–Miyaura cross-coupling enabled synthesis of novel arylated benzofuran-triazole hybrids

in Organic Chemistry

Muhammad Jawwad Saif
Sajjad Ahmad
Aqsa Mushtaq
Saba Munawar
Ameer Fawad Zahoor
Shoela Ettampola
Ali Irfan
Katarzyna Kotwica-Mojzych
Karol Ruszel
Mariusz Mojzych

Frontiers in Chemistry

doi 10.3389/fchem.2025.1726528

1,527 views

Original Research

Published on 21 Nov 2025

Extraction of tobacco extract from discarded tobacco leaves for cigarette yarns dyeing and neophytadiene separation

in Organic Chemistry

Long Wang
Weihua Chen
Yuqi Wan
Aimin He
Jiayin Liu
Xuemin Hu

Frontiers in Chemistry

doi 10.3389/fchem.2025.1682505

1,448 views

Editorial

Published on 16 Oct 2025

Editorial: Recent advances in synthetic organic chemistry at the biomedical interface: honoring Professor Iwao Ojima on the occasion of his 80th birthday

in Organic Chemistry

Thierry Brigaud
Greta Varchi

Frontiers in Chemistry

doi 10.3389/fchem.2025.1721249

1,565 views

Original Research

Published on 23 Sep 2025

A streamlined synthetic approach to the truncated linear trisaccharide fragment of QS-21

in Organic Chemistry

Jhe-Sian Lin
Zheng-Hao Tzeng
Jasper S. Dumalaog
Shang-Cheng Hung

Frontiers in Chemistry

doi 10.3389/fchem.2025.1650302

3,947 views

Original Research

Published on 04 Sep 2025

Formal synthesis of dibenzotetrathiafulvalene (DBTTF), through practical electrochemical preparation of benzo[d]-1,3-dithiole-2-one (BDTO)

in Organic Chemistry

Álvaro V. Terán-Alcocer
Fernanda M. J. Cifuentes-Ajuchan
Byron J. López-Mayorga
Bernardo A. Frontana-Uribe

Frontiers in Chemistry

doi 10.3389/fchem.2025.1666772

2,811 views

Original Research

Published on 14 Jul 2025

Magnetic nanocatalyst for microwave-assisted synthesis of Benzo[4,5]imidazo[1,2-a]pyrimidines via A3 coupling

in Organic Chemistry

Yuqiang Pan

Frontiers in Chemistry

doi 10.3389/fchem.2025.1631183

3,476 views

Review

Published on 30 May 2025

Transition metal supported UiO-67 materials and their applications in catalysis

in Organic Chemistry

Tingting Li
Yan Li
Jingxin Mao

Frontiers in Chemistry

doi 10.3389/fchem.2025.1596868

5,415 views
2 citations

Editorial

Published on 02 Apr 2025

Editorial: Five-membered ring heterocyclic compounds as anticancer drug candidates

in Organic Chemistry

Arif Mermer
İlkay Erdogan Orhan
Gang Ye
Nv Anil Kumar
Ramona Danac

Frontiers in Chemistry

doi 10.3389/fchem.2025.1599140

3,234 views
3 citations

Review

Published on 28 Mar 2025

Application of Hosomi-Sakurai allylation reaction in total synthesis of biologically active natural products

in Organic Chemistry

Justice Akwensi
Robert T. Kumah
Dorcas Osei-Safo
Richard K. Amewu

Frontiers in Chemistry

doi 10.3389/fchem.2025.1527387

4,995 views
1 citation

Original Research

Published on 19 Mar 2025

Iron ore pellets based-Ag2O nanoparticles as efficient Bi-functional heterogeneous catalyst for the synthesis tetrahydrobenzo[α]xanthens in green media

in Organic Chemistry

Ehsan Faryabi
Enayatollah Sheikhhosseini
Mahdieh Yahyazadehfar

Frontiers in Chemistry

doi 10.3389/fchem.2025.1413080

1,765 views

Original Research

Published on 17 Mar 2025

Iridoid glycoside dimers from fruits of Cornus officinalis and their anti-inflammatory activity

in Organic Chemistry

Ying-Chu Shi
Yu-Xin Yu
Jiu-Xia Gao
Xin Wang
Xiao-Ya Shang
Jia Xu

Frontiers in Chemistry

doi 10.3389/fchem.2025.1558075

2,287 views
3 citations

Review

Published on 03 Mar 2025

Recent achievements in synthesis of anthracene scaffolds catalyzed transition metals

in Organic Chemistry

Fadhil Faez Sead
Vicky Jain
R. Roopashree
Aditya Kashyap
Suman Saini
Girish Chandra Sharma
Pushpa Negi Bhakuni
Mosstafa Kazemi
Ramin Javahershenas

Frontiers in Chemistry

doi 10.3389/fchem.2025.1545252

8,142 views
13 citations

Original Research

Published on 28 Feb 2025

Design, synthesis, in silico studies and antiproliferative evaluation of some novel hybrids of pyrimidine-morpholine

in Organic Chemistry

Elaheh Ataollahi
Leila Emami
Al-Anood Mohammad Al-Dies
Fateme Zare
Alireza Poustforoosh
Mina Emami
Fateme Saadat
Fateme Motamen
Zahra Rezaei
Soghra Khabnadideh

Frontiers in Chemistry

doi 10.3389/fchem.2025.1537261

8,660 views
3 citations

Original Research

Published on 21 Jan 2025

Design and synthesis of phenylthiophosphoryl dichloride derivatives and evaluation of their antitumour and anti-inflammatory activities

in Organic Chemistry

Chunyun Xu
Na Yang
Haichun Yu
Xiaojing Wang

Frontiers in Chemistry

doi 10.3389/fchem.2024.1529211

2,033 views
3 citations

Original Research

Published on 17 Dec 2024

Oxidative coupling of N-nitrosoanilines with substituted allyl alcohols under rhodium (III) catalysis

in Organic Chemistry

Priyanka Chaudhary

Frontiers in Chemistry

doi 10.3389/fchem.2024.1506493

2,770 views

Review

Published on 13 Dec 2024

Novel transition metal-free synthetic protocols toward the construction of 2,3-dihydrobenzofurans: a recent update

in Organic Chemistry

Aqsa Mushtaq
Muhammad Irfan
Atta ul Haq
Asim Mansha
Samreen Gul Khan
Ameer Fawad Zahoor
Bushra Parveen
Ali Irfan
Katarzyna Kotwica-Mojzych
Mariola Glowacka

Frontiers in Chemistry

doi 10.3389/fchem.2024.1470861

6,946 views
2 citations

Editorial

Published on 03 Dec 2024

Editorial: Spotlight on North America – chemical sciences

in Organic Chemistry

Subhash C. Sinha
Chinna Rajesh Ummadisetti
Kenneth K. Laali
Kai Bao
Naga V. S. D. K. Bhupathiraju
Iwao Ojima

Frontiers in Chemistry

doi 10.3389/fchem.2024.1531189

1,515 views

Original Research

Published on 25 Nov 2024

Sustainable synthesis of antibacterial 3-aryl-2H-benzo[b,1,4]oxazin-2-ones via SNAr Csp2–Csp2 coupling

in Organic Chemistry

Fatemeh Salehzadeh
Maryam Esmkhani
Milad Noori
Shahrzad Javanshir
Aida Iraji
Mohammad Mahdavi

Frontiers in Chemistry

doi 10.3389/fchem.2024.1472342

3,455 views
1 citation

Original Research

Published on 14 Nov 2024

Synthesis of branched and linear galactooligosaccharides related to glucuronoxylomannogalactan of Cryptococcus neoformans

in Organic Chemistry

Vera S. Dorokhova
Bozhena S. Komarova
José O. Previato
Lúcia Mendonça Previato
Vadim B. Krylov
Nikolay E. Nifantiev

Frontiers in Chemistry

doi 10.3389/fchem.2024.1501766

2,132 views
3 citations