Frontiers in Immunology | Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Editorial

Published on 15 Dec 2025

Editorial: Exploring immune-stromal cell dynamics: pathways and therapeutic implications

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Stacy Ryu
Stephen B Gauld
Matthew M Staron
Ian D Odell
Jenna L Cash
Timothy RDJ Radstake

Frontiers in Immunology

doi 10.3389/fimmu.2025.1744273

1,131 views

Review

Published on 15 Dec 2025

Macrophages: friend or foe in diabetes pathogenesis and therapy

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Rachel N. Grimes
Marco Orecchioni
Estefania Quesada-Masachs

Frontiers in Immunology

doi 10.3389/fimmu.2025.1625391

2,418 views

Review

Published on 15 Dec 2025

Co-occurrence of autoimmune diseases and metabolic disorders in familial mediterranean fever patients: review of literature and case reports

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Ahlam Chaaban
Nohad Baalbaki
Ralph Narch
Eliana Eldawra
Philippe Hussein Kobeissy
José-Noel Ibrahim

Frontiers in Immunology

doi 10.3389/fimmu.2025.1726664

1,906 views

Original Research

Published on 11 Dec 2025

MMP-9 affects dural cell composition and granulocyte accumulation during neuroinflammation

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Sheng-Hsiang Shen
Hanna Gerwien
Miriam Burmeister
Yi-Ling Tsang
I-Na Lu
Anna-Lena Börsch
Tushar Deshpande
Lydia Sorokin
Gerd Meyer zu Hörste

Frontiers in Immunology

doi 10.3389/fimmu.2025.1713166

2,203 views

Original Research

Published on 11 Dec 2025

Therapeutic drug monitoring plays an important role in patients with noninfectious uveitis receiving adalimumab

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Weidong Cheng
Jiayu Xiao
Shengjie Li
Huaru Wang
Shasha Wang
Yujing Qian
Chan Zhao
Fei Gao
Xuzhen Qin
Meifen Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1733644

921 views

Review

Published on 11 Dec 2025

Experimental animal models of acute respiratory distress syndrome: one-hit and two-hit establishment application

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Yue Zhao
Xin Li
Yanhua Ou
Xiangran Cai
Weijian Huang
Shuhua He
Sisi Liang
Ning Wang
Linliang Song
Meixia Fang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1649074

1,365 views

Review

Published on 10 Dec 2025

Research progress on the application of nanobodies in immunity and infectious skin diseases

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Liguo Qiu
Fengming Hu
Xiaohua Tao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1705553

1,424 views

Case Report

Published on 10 Dec 2025

IgG4-related disease presenting with hypercalcemia: case report and mechanistic insights

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Yaxin Li
Xing Niu
Ling Li
Zhangxue Hu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1720791

1,385 views

Perspective

Published on 09 Dec 2025

Cross-talk between aging resilience pathways and autoimmunity onset

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Rahul Mittal
Danay Saavedra
Mannat Mittal
Khemraj Hirani

Frontiers in Immunology

doi 10.3389/fimmu.2025.1712575

1,757 views

Original Research

Published on 08 Dec 2025

A 20-year real-world study on drug survival and predictive factors for infliximab discontinuation in Behçet’s syndrome

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Rosaria Talarico
Antonello Sulis
Federica Di Cianni
Diana Marinello
Maria Laura Manca
Marta Mosca

Frontiers in Immunology

doi 10.3389/fimmu.2025.1726690

1,425 views

Brief Research Report

Published on 04 Dec 2025

A data-driven model of macrophage polarization states reveals an IFN macrophage signature in active Crohn’s disease

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Sarina C. Lowe
Madelaine Leitman
Noah Yan
Alexander Hoffmann

Frontiers in Immunology

doi 10.3389/fimmu.2025.1707719

1,416 views

Mini Review

Published on 03 Dec 2025

Beyond the joints: mechanistic insights and multidisciplinary strategies for spondyloarthritis-associated uveitis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Shuyue Pan
Ling Xiang
Zhi Cao
Zhi Yang
Rui-Juan Cheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1715107

1,232 views

Brief Research Report

Published on 02 Dec 2025

VEXAS syndrome in rheumatology practice: features from a multicenter cohort in north-east Italy

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Sara Bindoli
Greta Morello-Pasin
Irina Guidea
Roberto Padoan
Luca Iorio
Riccardo Bixio
Giovanni Orsolini
Federica Maiolini
Sara Lombardi
Sandra Lombardi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1700737

1,531 views

Original Research

Published on 02 Dec 2025

Serum and urine anti-PLA2R antibody correlation with albuminuria in idiopathic membranous nephropathy

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Xiaogang Liu
Yunfei Fu
Manshu Sui
Xuehua Wang
Zizhen Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1670960

1,302 views

Case Report

Published on 28 Nov 2025

Case Report: VEXAS syndrome with extensive pulmonary, cardiac, and skeletal involvement

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Zhongbiao Fang
Tingwei Xu
Meng Zhang
Chaonan Li
Anwen Zheng
Yudan Gu
Chuhan Lan
Zongming Liu
Lingling Tang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1724045

1,598 views

Original Research

Published on 27 Nov 2025

Single-cell transcriptomic analysis reveals a systemic immune dysregulation in intravenous immunoglobulin non-responsive Kawasaki disease

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Chenhui Feng
Qirui Li
Minna Yang
Yeshi Chen
Mingming Zhang
Hongmao Wang
Xiaohui Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1702290

1,587 views
1 citation

Original Research

Published on 26 Nov 2025

A machine learning algorithm to predict treatment effectiveness for Kawasaki disease in China: a retrospective model development and validation study

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Xuemei Li
Zihan Zhou
Jingyi Fan
Lin Zhao
Ruidi Xu
Dong Li
Xu Ma
Lu Sun
Yujian Wu
Zhouping Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1629600

3,352 views

Review

Published on 25 Nov 2025

Citrullinated peptides as drug candidates for rheumatoid arthritis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Adrian H. Bustos
Mads Brüner
Tue Wenzel Kragstrup
Kira Astakhova

Frontiers in Immunology

doi 10.3389/fimmu.2025.1648913

2,594 views

Case Report

Published on 21 Nov 2025

Case Report: Exploring the underlying mechanisms of psoriasis comorbid with sarcoidosis: insights from a case of coexisting immune-related disorders

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Yingbao Zhen
Xinlin Liang
Dawei Huang
Yangfeng Ding
Yuling Shi
Qian Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1685695

988 views

Review

Published on 21 Nov 2025

The complex interplay between psoriasis and depression: from molecular mechanisms to holistic treatment approaches

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Ying Wang
Jianxiao Xing
Yanyang Liang
Huifang Liang
Xuping Niu
Junqin Li
Kaiming Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1659346

2,892 views
1 citation

Original Research

Published on 21 Nov 2025

Different phenotypes of severe flares in patients with systemic lupus erythematosus: results of a clustering analysis in a monocentric cohort

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

E. Elefante
D. Schilirò
M. L. Manca
C. Stagnaro
D. Zucchi
C. Cardelli
V. Signorini
M. Maffi
G. Cascarano
R. Zas

Frontiers in Immunology

doi 10.3389/fimmu.2025.1673350

1,786 views

Original Research

Published on 21 Nov 2025

Exploring the role of NOD2 variants in pediatric undifferentiated recurrent fever: a clinical and functional perspective

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Raziye Burcu Taşkın
Arzum Hande Kamiloğlu
Buşra Bara
Gizem Akyol
İlyas Aydın
Gulcin Aytac
Neslihan Edeer Karaca
Güzide Aksu
Afig Berdeli
Vildan Bozok

Frontiers in Immunology

doi 10.3389/fimmu.2025.1657782

1,587 views

Review

Published on 18 Nov 2025

γδ T cells in diabetes mellitus: dual roles and therapeutic implications

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Bing Wang
Qi Li
Qiuyue Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1693466

2,077 views

Case Report

Published on 18 Nov 2025

Upadacitinib in the treatment of SAPHO syndrome: a case report

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Yanran Yang
Zhanxue Sun
Yongpeng Ge

Frontiers in Immunology

doi 10.3389/fimmu.2025.1662675

1,767 views

551 articles

articles

Editorial: Exploring immune-stromal cell dynamics: pathways and therapeutic implications

Macrophages: friend or foe in diabetes pathogenesis and therapy

Co-occurrence of autoimmune diseases and metabolic disorders in familial mediterranean fever patients: review of literature and case reports

MMP-9 affects dural cell composition and granulocyte accumulation during neuroinflammation

Therapeutic drug monitoring plays an important role in patients with noninfectious uveitis receiving adalimumab

Experimental animal models of acute respiratory distress syndrome: one-hit and two-hit establishment application

Research progress on the application of nanobodies in immunity and infectious skin diseases

IgG4-related disease presenting with hypercalcemia: case report and mechanistic insights

Cross-talk between aging resilience pathways and autoimmunity onset

A 20-year real-world study on drug survival and predictive factors for infliximab discontinuation in Behçet’s syndrome

A data-driven model of macrophage polarization states reveals an IFN macrophage signature in active Crohn’s disease

Beyond the joints: mechanistic insights and multidisciplinary strategies for spondyloarthritis-associated uveitis

VEXAS syndrome in rheumatology practice: features from a multicenter cohort in north-east Italy

Serum and urine anti-PLA2R antibody correlation with albuminuria in idiopathic membranous nephropathy

Case Report: VEXAS syndrome with extensive pulmonary, cardiac, and skeletal involvement

Single-cell transcriptomic analysis reveals a systemic immune dysregulation in intravenous immunoglobulin non-responsive Kawasaki disease

A machine learning algorithm to predict treatment effectiveness for Kawasaki disease in China: a retrospective model development and validation study

Citrullinated peptides as drug candidates for rheumatoid arthritis

Case Report: Exploring the underlying mechanisms of psoriasis comorbid with sarcoidosis: insights from a case of coexisting immune-related disorders

The complex interplay between psoriasis and depression: from molecular mechanisms to holistic treatment approaches

Different phenotypes of severe flares in patients with systemic lupus erythematosus: results of a clustering analysis in a monocentric cohort

Exploring the role of NOD2 variants in pediatric undifferentiated recurrent fever: a clinical and functional perspective

γδ T cells in diabetes mellitus: dual roles and therapeutic implications

Upadacitinib in the treatment of SAPHO syndrome: a case report