Frontiers in Pharmacology | Inflammation Pharmacology

Original Research

Published on 23 Apr 2025

An off-target effect of class A CpG-oligonucleotides on suppressing the cyclic GMP-AMP synthase signaling in fibroblastic reticular cells

in Inflammation Pharmacology

Preethi Jayakumar
Ting Jiang
Hai Huang
Meihong Deng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1576151

780 views

Review

Published on 16 Apr 2025

Mechanism underlying the involvement of CXCR4/CXCL12 in diabetic wound healing and prospects for responsive hydrogel-loaded CXCR4 formulations

in Inflammation Pharmacology

Lingli Wang
Fengsong Nie
Zhaoyu Lu
Yang Chong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1561112

934 views

Original Research

Accepted on 14 Apr 2025

Signal mining and analysis of sepsis-related adverse events in patients using immunosuppressive drugs based on the FDA Adverse Event Reporting System(FAERS)database

in Inflammation Pharmacology

XueHui Zhou
Hao Chen
Qiao-Lian Xu
Jia-Kui Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1598433

156 views

Original Research

Published on 09 Apr 2025

Umbilical cord stem cells therapy against bacterial pneumonia based on zebrafish pneumonia model

in Inflammation Pharmacology

Xueli Chen
Jian Jin
Xia Chen
Yabin Wu
Youjun Guo
Zuoyu Qian
Hui Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1546193

718 views

Review

Published on 09 Apr 2025

Oxidative stress in vascular surgical diseases: mechanisms, impacts and therapeutic perspectives

in Inflammation Pharmacology

Haosen Xu
Jin Yang
Zhanhui Wei
Shijie Bao
Zhuo Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1527684

847 views

Review

Published on 08 Apr 2025

Anti-inflammatory drugs as potential antimicrobial agents: a review

in Inflammation Pharmacology

Onyedika Emmanuel Okpala
Johana Rondevaldova
Ladislav Kokoska

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1557333

2,789 views

Review

Published on 07 Apr 2025

Paeoniflorin: a review of its pharmacology, pharmacokinetics and toxicity in diabetes

in Inflammation Pharmacology

Xue Ou
Zhijie Yu
Chuanyu Pan
Xi Zheng
Dandan Li
Zhenzhen Qiao
Xiaoyuan Zheng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1551368

1,317 views

Review

Published on 07 Apr 2025

Research progress on the mechanism of curcumin anti-oxidative stress based on signaling pathway

in Inflammation Pharmacology

Jie Cui
Haonan Li
Tianyi Zhang
Fengli Lin
Meiyun Chen
Guimin Zhang
Zhong Feng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1548073

1,414 views

Review

Published on 04 Apr 2025

The emerging role of vascular endothelial cell-mediated angiogenesis in the imbalance of RA synovial microenvironment and its clinical relevance

in Inflammation Pharmacology

Xingxing Huo
Yanhui Peng
Hui Li
Chen Li
Faxue Liao
Chenggui Miao
Yurong Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1481089

826 views

Original Research

Published on 03 Apr 2025

Exploring the mechanism of triptolide inhibiting the motility of fibroblast-like synoviocytes in rheumatoid arthritis via RhoA/Rho-associated kinase axis, based on network pharmacology, molecular docking and molecular dynamics simulations

in Inflammation Pharmacology

Jiacheng Shen
Yuxuan Fang
Nan Xu
Hongyi Chen
Miao Zhu
Dan Li
Zewen Chu
Masataka Sunagawa
Yanqing Liu
Haibo Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1545514

1,619 views
1 citation

Original Research

Published on 03 Apr 2025

Circ_0098181 binds PKM2 to attenuate liver fibrosis

in Inflammation Pharmacology

Yuan-Yuan Luo
Ya-Ping Guan
Hong-Fei Zhan
Chun-Yan Sun
Ling-Yan Cai
Ke-Gong Tao
Yong Lin
Xin Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1517250

1,079 views

Original Research

Published on 02 Apr 2025

Dynamic risk stratification and treatment optimization in sepsis: the role of NLPR

in Inflammation Pharmacology

Qiqi Chen
Ming Zhang
Yuxin Xia
Ya Deng
Yanna Yang
Lili Dai
Hongxia Niu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1572677

1,634 views
1 citation

Original Research

Published on 01 Apr 2025

Metal-phenolic nanozyme as a ferroptosis inhibitor for alleviating cisplatin-induced acute kidney injury

in Inflammation Pharmacology

Yunfeng Xiong
Huimin Kang
Yanping Rao
Xiayu Huang
Yang Zhu
Lixin Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1535969

1,096 views

Clinical Trial

Published on 01 Apr 2025

First-in-human study of CPL’116 – a dual JAK/ROCK inhibitor – in healthy subjects

in Inflammation Pharmacology

Piotr J. Rudzki
Katarzyna Jarus-Dziedzic
Dorota Włodarczyk
Michał Kaza
Piotr Pankiewicz
Agnieszka Gierczak-Pachulska
Martyna Banach
Beata Zygmunt
Cezary Piwowarczyk
Paweł Żero

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1583723

1,036 views

Original Research

Published on 01 Apr 2025

A real-world pharmacovigilance analysis of omadacycline in FDA adverse event reporting system (FAERS) database

in Inflammation Pharmacology

Xueping Shi
Chen Wang
Xiang Liu
Li Zou
Pei Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1558868

1,383 views

Review

Published on 01 Apr 2025

Region-specific mitophagy in nucleus pulposus, annulus fibrosus, and cartilage endplate of intervertebral disc degeneration: mechanisms and therapeutic strategies

in Inflammation Pharmacology

Chaoqun Feng
Ziang Hu
Min Zhao
Chuan Leng
Guangye Li
Fei Yang
Xiaohong Fan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1579507

1,774 views