Frontiers in Pharmacology | Pharmacogenetics and Pharmacogenomics

Review

Published on 20 Mar 2025

Deciphering gene mutations in the efficacy and toxicity of antineoplastic drugs: an oncology pharmacist’s perspective

in Pharmacogenetics and Pharmacogenomics

Yucai Jiang
Guolin Alexander Wen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1574010

785 views

Original Research

Published on 19 Mar 2025

Impact of CYP3A4 and ABCB1 genetic variants on tacrolimus dosing in Greek kidney transplant recipients

in Pharmacogenetics and Pharmacogenomics

Anna Tsironi
Konstantinos Lazaros
Effrosyni Mendrinou
Marios Papasotiriou
Stavroula Siamoglou
Kyriaki Kydonopoulou
Anne John
Alexandra Gerou
Spyridon Gerou
Bassam R. Ali

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1538432

1,165 views

Editorial

Published on 17 Mar 2025

Editorial: Multi-omics technology: revealing the pathogenesis of diseases and the mechanism of drug efficacy of major diseases such as nutritional metabolism disorders and mental disorders

in Pharmacogenetics and Pharmacogenomics

Wenzhi Hao
Tianhao Liu
Xiliang Du
Gabriel Tao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1586223

383 views

Original Research

Published on 17 Mar 2025

Comprehensive pharmacogenomics profiling of the Serbian population

in Pharmacogenetics and Pharmacogenomics

Marina Jelovac
Djordje Pavlovic
Biljana Stankovic
Nikola Kotur
Bojan Ristivojevic
Sonja Pavlovic
Branka Zukic

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1553536

619 views

Brief Research Report

Published on 11 Mar 2025

Effect of CYP3A5 genotypes on pharmacokinetic of tacrolimus in colombian liver transplant patients

in Pharmacogenetics and Pharmacogenomics

Erica Fernanda Lindarte
Gonzalo De Jesus Vasquez
Luis Guillermo Toro Rendón
Andrés Felipe Zuluaga Salazar
Jefferson Antonio Buendia

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1505490

495 views

Original Research

Published on 05 Mar 2025

Allele and genotype frequencies of variants in P450 cytochromes, transports, and DNA repair enzymes in the Dominican Republic population

in Pharmacogenetics and Pharmacogenomics

Elizabeth Pérez-Duval
Berniza Calderón
Marlen Izquierdo
José A. Herrera-Isidrón
Elizabeth Reyes-Reyes
Alejandro Herrera
Manuel Soto
Alba Beltré
Idania Rodeiro-Guerra

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1494482

781 views

Review

Published on 03 Mar 2025

Genome-wide functional annotation of variants: a systematic review of state-of-the-art tools, techniques and resources

in Pharmacogenetics and Pharmacogenomics

Eleftherios Pilalis
Dimitrios Zisis
Christina Andrinopoulou
Theodora Karamanidou
Maria Antonara
Thanos G. Stavropoulos
Aristotelis Chatziioannou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1474026

1,182 views

Mini Review

Published on 27 Feb 2025

Precision medicine in colorectal cancer: genomics profiling and targeted treatment

in Pharmacogenetics and Pharmacogenomics

Adi Muradi Muhar
Adrian Joshua Velaro
Arya Tjipta Prananda
Sony Eka Nugraha
Princella Halim
Rony Abdi Syahputra

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532971

870 views

Original Research

Published on 21 Feb 2025

The CYP2D6 phenotyping performance of single-point saliva metabolic ratio in a healthy Chinese Han population

in Pharmacogenetics and Pharmacogenomics

Yongfa Huang
Zhangyuting He
Xiaoduo Guan
Pei Hu
Rui Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1438760

610 views

Mini Review

Published on 12 Feb 2025

Association between CYP2C19 polymorphism and proton pump inhibitors adverse drug reactions: a narrative review

in Pharmacogenetics and Pharmacogenomics

Asmaa Ibrahim
Kazeem Yusuff
Ahmed Awaisu
Hazem Elewa

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1523399

841 views

Original Research

Published on 03 Feb 2025

Leveraging AI to automate detection and quantification of extrachromosomal DNA to decode drug responses

in Pharmacogenetics and Pharmacogenomics

Kohen Goble
Aarav Mehta
Damien Guilbaud
Jacob Fessler
Jingting Chen
William Nenad
Christina G. Ford
Oliver Cope
Darby Cheng
William Dennis

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1516621

1,247 views

Original Research

Published on 30 Jan 2025

Deciphering the heterogeneity and plasticity of the tumor microenvironment in liver cancer provides insights for prognosis

in Pharmacogenetics and Pharmacogenomics

Yihao Sun
Guojuan Shi
Jian Yang
Chun-Zhong Zhou
Chuhan Peng
Yu-Hong Luo
Ying Pan
Rui-Qi Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1495280

1,137 views

Review

Published on 29 Jan 2025

Uncovering the role of microRNAs in esophageal cancer: from pathogenesis to clinical applications

in Pharmacogenetics and Pharmacogenomics

Zhenglin He
Yishuo Ji
Yutong Yuan
Tianfang Liang
Chenglin Liu
Yiping Jiao
Yimeng Chen
Yiming Yang
Liang Han
Yue Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532558

1,277 views

Original Research

Published on 22 Jan 2025

Better understanding the phenotypic effects of drugs through shared targets in genetic disease networks

in Pharmacogenetics and Pharmacogenomics

Elena Díaz-Santiago
Aurelio A. Moya-García
Jesús Pérez-García
Raquel Yahyaoui
Christine Orengo
Florencio Pazos
James R. Perkins
Juan A. G. Ranea

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1470931

1,065 views

Original Research

Published on 07 Jan 2025

Pharmacogenetic and pharmacokinetic factors for dexmedetomidine-associated hemodynamic instability in pediatric patients

in Pharmacogenetics and Pharmacogenomics

Yanping Guan
Bilian Li
Yiyu Zhang
Hao Luo
Xueding Wang
Xue Bai
Zhuoling Zheng
Yaying Huang
Wei Wei
Min Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1515523

911 views

Editorial

Published on 03 Jan 2025

Editorial: Insights in pharmacogenetics and pharmacogenomics: 2023

in Pharmacogenetics and Pharmacogenomics

José A. G. Agúndez
Elena García-Martín

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1540478

546 views