Frontiers in Pharmacology | Pharmacogenetics and Pharmacogenomics

Original Research

Published on 15 Aug 2025

Population-specific genetic differences of acute coronary syndrome in Han and Uyghur Chinese

in Pharmacogenetics and Pharmacogenomics

Hongmei Lai
Jinhang Zhu
Jing Tao
Zitong Guo
Xiaolin Yu
Xin Shen
Ting Wang
Ying Wang
Huan Cai
Xiao Cai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1588658

480 views

Original Research

Accepted on 14 Aug 2025

A Multi-Centre Observational Cohort Study on Pharmacogenomic Predictors of Rosuvastatin Discontinuation in a Multiethnic Population

in Pharmacogenetics and Pharmacogenomics

Mais Alqasrawi
Zeina Nizar Al-Mahayri
Lubna Khasawneh
Areej AlBawa’neh
Lilas Dabaghie
Sahar M. Altoum
Dana Hamza
Salahdein Aburuz
Virendra Misra
Gohar Jamil

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1656520

125 views

Brief Research Report

Accepted on 12 Aug 2025

Comparative evaluation of Oxford Nanopore Technologies' adaptive sampling and the Twist long-read PGx panel for pharmacogenomic profiling

in Pharmacogenetics and Pharmacogenomics

Koen Deserranno
Laurentijn Tilleman
Dieter Deforce
Filip Van Nieuwerburgh

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1653999

143 views

Review

Published on 12 Aug 2025

Role of pharmacogenomics for prevention of hypersensitivity reactions induced by aromatic antiseizure medications

in Pharmacogenetics and Pharmacogenomics

Angel T. Alvarado
Amparo Iris Zavaleta
César Li-Amenero
María R. Bendezú
Jorge A. Garcia
Haydee Chávez
Juan J. Palomino-Jhong
Felipe Surco-Laos
Doris Laos-Anchante
Elizabeth J. Melgar-Merino

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1640401

361 views

Correction

Published on 08 Aug 2025

Correction: Overexpression of Nrf2 in bone marrow mesenchymal stem cells promotes B-cell acute lymphoblastic leukemia cells invasion and extramedullary organ infiltration through stimulation of the SDF-1/CXCR4 axis

in Pharmacogenetics and Pharmacogenomics

Lin Zheng
Chengyun Pan
Dan Ma
Qin Shang
Tianzhen Hu
Tianzhuo Zhang
Qian Kang
Xiuying Hu
Shuyun Cao
Li Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1660169

271 views

Review

Published on 07 Aug 2025

Global variation in antibiotic prescribing guidelines and the implications for decreasing AMR in the future

in Pharmacogenetics and Pharmacogenomics

Emmama Jamil
Zikria Saleem
Brian Godman
Matti Ullah
Afreenish Amir
Abdul Haseeb
Johanna C. Meyer
Muhammad Usman Qamar
Safa S. Almarzoky Abuhussain

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1600787

1,150 views

Review

Published on 07 Aug 2025

The role and challenges of intratumoral microbiota in colorectal cancer immunotherapy

in Pharmacogenetics and Pharmacogenomics

Miao Hao
Haiming Xu
Min Li
Dan Jiao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1634703

404 views

Clinical Trial

Published on 07 Aug 2025

Clinicians’ experience on the effectiveness of pharmacotherapy in patients with first-episode depression: a randomized controlled trial based on pharmacogenomics

in Pharmacogenetics and Pharmacogenomics

Jie Tong
Jie Yuan
Yu Qin
Na Zhu
Tingting Zhang
Xiaochun Zhu
Yuanyuan Xu
Meilin Liu
Jie Zhang
Xirong Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1626654

286 views

Original Research

Accepted on 05 Aug 2025

Prevalence of risk phenotypes associated with CYP2C92, 3 and VKORC1 c.-1639G>A genetic polymorphisms in the world populations: Implications in clinical practice

in Pharmacogenetics and Pharmacogenomics

Dr. Mohitosh Biswas
Murshadul Alam Murad
Maliheh Ershadian
Most. Sumaiya Khatun Kali
Maw Shin Sim
Baharudin Ibrahim
CHONLAPHAT SUKASEM

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1597379

111 views

Review

Accepted on 29 Jul 2025

Epigenetic Regulation of Bladder Cancer in the Context of Aging

in Pharmacogenetics and Pharmacogenomics

Xuewei Liu
Guofeng Ding
Yifan Liu
Xiaoli Yan
Yan Zhao
Hailin Lv
Xiaojuan Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1617452

409 views

Original Research

Accepted on 28 Jul 2025

The prevalence of Ggenetic variants of the Mas-related G-proteincoupled receptor X2 in patients experiencing does not explain perioperative hypersensitivity reactions to neuromuscular blocking agents

in Pharmacogenetics and Pharmacogenomics

Alicja Dziadowiec
Mateusz Kwitniewski
Peter Kopac
Hubert Aleksander Rybka
Lenka Sedlackova
Adriana Srotova
Wojciech Dyga
Joanna Gluck
Radoslaw Kitel
Grzegorz Porebski

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1655722

263 views

Original Research

Published on 21 Jul 2025

Clinical significance and gene prediction of a novel classification system based on tacrolimus concentration-to-dose ratio in the early post-liver transplant period

in Pharmacogenetics and Pharmacogenomics

Junwei Fan
Peihao Wen
Liyun Yuan
Yan Xia
Shijie Hu
Xiaoqing Zhang
Zhihai Peng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1614753

790 views

Original Research

Accepted on 20 Jul 2025

Analysis of six CYP450 genetic variants regarding the response to Cannabidiol combined with anticonvulsant medication in Mexican patients with drug-resistant epilepsy

in Pharmacogenetics and Pharmacogenomics

Iris Angelica Feria-Romero
Luisa Lilia Rocha
Araceli Reyes-Cuayahuitl
Iris E. Martínez-Juárez
DANIEL SAN-JUAN
CONSUELO ESCAMILLA-NUÑEZ
Sandra Orozco-Suárez

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1626054

225 views

Mini Review

Published on 17 Jul 2025

Statins and their impact on epigenetic regulation: insights into disease

in Pharmacogenetics and Pharmacogenomics

Rafael Tamayo-Trujillo
Patricia Guevara-Ramírez
Santiago Cadena-Ullauri
Viviana A. Ruiz Pozo
Elius Paz-Cruz
Ana Karina Zambrano

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1621163

1,267 views

Review

Published on 16 Jul 2025

Epigenetic modifications of gut microbiota and their potential role in atherosclerosis

in Pharmacogenetics and Pharmacogenomics

Shuang Guo
Junlai Zhao
Rongrong Zhu
Zhi Fan
Shibiao Liu
Weiwei Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1638240

1,031 views

Systematic Review

Published on 16 Jul 2025

Polymorphisms in CYP3A5, CYP3A4, and ABCB1 genes: implications for calcineurin inhibitors therapy in hematopoietic cell transplantation recipients—a systematic review

in Pharmacogenetics and Pharmacogenomics

Luiz Carlos da Costa-Junior
Daniely Regina Freitas-Alves
Amanda Melo Leite Leão
Hayra de Andrade Vieira Monteiro
Rita de Cássia Barbosa da Silva Tavares
Maria Claudia Rodrigues Moreira
Marília Berlofa Visacri
Teresa de Souza Fernandez
Paulo Caleb Júnior de Lima Santos

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1569353

1,194 views

Population-specific genetic differences of acute coronary syndrome in Han and Uyghur Chinese

A Multi-Centre Observational Cohort Study on Pharmacogenomic Predictors of Rosuvastatin Discontinuation in a Multiethnic Population

Comparative evaluation of Oxford Nanopore Technologies' adaptive sampling and the Twist long-read PGx panel for pharmacogenomic profiling

Role of pharmacogenomics for prevention of hypersensitivity reactions induced by aromatic antiseizure medications

Correction: Overexpression of Nrf2 in bone marrow mesenchymal stem cells promotes B-cell acute lymphoblastic leukemia cells invasion and extramedullary organ infiltration through stimulation of the SDF-1/CXCR4 axis

Global variation in antibiotic prescribing guidelines and the implications for decreasing AMR in the future

The role and challenges of intratumoral microbiota in colorectal cancer immunotherapy

Clinicians’ experience on the effectiveness of pharmacotherapy in patients with first-episode depression: a randomized controlled trial based on pharmacogenomics

Prevalence of risk phenotypes associated with CYP2C9*2, *3 and VKORC1 c.-1639G>A genetic polymorphisms in the world populations: Implications in clinical practice

Epigenetic Regulation of Bladder Cancer in the Context of Aging

The prevalence of Ggenetic variants of the Mas-related G-proteincoupled receptor X2 in patients experiencing does not explain perioperative hypersensitivity reactions to neuromuscular blocking agents

Clinical significance and gene prediction of a novel classification system based on tacrolimus concentration-to-dose ratio in the early post-liver transplant period

Analysis of six CYP450 genetic variants regarding the response to Cannabidiol combined with anticonvulsant medication in Mexican patients with drug-resistant epilepsy

Statins and their impact on epigenetic regulation: insights into disease

Epigenetic modifications of gut microbiota and their potential role in atherosclerosis

Polymorphisms in CYP3A5, CYP3A4, and ABCB1 genes: implications for calcineurin inhibitors therapy in hematopoietic cell transplantation recipients—a systematic review

Prevalence of risk phenotypes associated with CYP2C92, 3 and VKORC1 c.-1639G>A genetic polymorphisms in the world populations: Implications in clinical practice