Frontiers in Pharmacology | Pharmacology of Infectious Diseases

Original Research

Accepted on 17 Oct 2025

A novel drug that reduces pneumococcal toxicity by targeting pneumolysin (PLY): efficacy of the traditional Chinese medicine Radix Paeoniae Alba

in Pharmacology of Infectious Diseases

Xu Yan
Jing Han
Yonglin Zhou
Liping Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1609457

129 views

Systematic Review

Accepted on 17 Oct 2025

Factors Affecting the Effectiveness and Safety of Colistin in Treating Drug-Resistant Gram-Negative Bacterial Infections: A Meta-Analysis

in Pharmacology of Infectious Diseases

Pengfei Li
Shiran Li
Jiao Zhang
Siyu Zeng
Zhimin Li
Jingxian Xie
Yong Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1625595

155 views

Original Research

Published on 17 Oct 2025

GEODE: an in silico tool that translates in vitro to in vivo predictions of tuberculosis antibiotic combination efficacy

in Pharmacology of Infectious Diseases

Maral Budak
Mariana Pereira Moraes
Talia Greenstein
Pauline Maiello
H. Jacob Borish
Harris B. Chishti
Kara Kracinovsky
Mark Rodgers
Jaime Tomko
Philana Ling Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1639673

1,248 views

Opinion

Accepted on 14 Oct 2025

Green-Synthesized Silver Nanoparticle Hydrogels for Biofilm-Infected Wounds: Bridging Sustainability and Clinical Translation

in Pharmacology of Infectious Diseases

M. Rifqi Fadillah Muslim
Lutfi Chabib
Betty Ekawati Suryaningsih

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1694144

197 views

Editorial

Published on 14 Oct 2025

Editorial: Multidrug resistant bacteria: new therapeutic approaches for a challenging problem

in Pharmacology of Infectious Diseases

Gabriela C. Fernández
Younes Smani
Sonia A. Gómez

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1712353

386 views

Original Research

Published on 10 Oct 2025

Optimizing antifungal dosing for invasive Cryptococcus infections: minimum inhibitory concentration distributions and pharmacokinetic/pharmacodynamic insights from 2010–2023 Antimicrobial Testing Leadership and Surveillance data

in Pharmacology of Infectious Diseases

Chia-Ying Liu
Chih-Cheng Lai
Chun-Chung Hsueh
Chih-Jen Weng
Wei-Lun Chang
Po-Ren Hsueh
Shio-Shin Jean

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1665253

726 views

Original Research

Accepted on 08 Oct 2025

Tigecycline pharmacodynamics in the hollow fiber system of Mycobacterium avium complex lung disease, and the utility of MICs and time-kill studies in drug development

in Pharmacology of Infectious Diseases

Devyani Deshpande
Shashikant Srivastava
Tawanda Gumbo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1682477

154 views

Study Protocol

Published on 08 Oct 2025

Yiqi Gubiao Pill for tuberculosis-associated obstructive pulmonary disease: protocol for a double-blind randomized controlled trial

in Pharmacology of Infectious Diseases

Jin Dai
Yifan Zhang
Jun Su
Guoxiang Yuan
Fengsen Li
Zhian Zhou
Aziza
Chunying Ye
Aznamu Seyiti
Maihesebu Pida

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1610889

973 views

Original Research

Accepted on 02 Oct 2025

Synthetic Bakuchiol Derivatives: Ester and Ether Analogues with Activity Against Clinically Important Bacteria

in Pharmacology of Infectious Diseases

Francisca Javiera Valdés Navarro
Evelyn Muñoz
Manuel Martinez-Lobos
Catalina Ferreria
Valentina Silva
Alejandro Madrid
Katy Díaz
Constanza Villarroel
Iván J. Montenegro

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1619997

179 views

Review

Published on 30 Sep 2025

Evaluating the advancements and efficacies in pharmacological Mpox treatments: a comprehensive review

in Pharmacology of Infectious Diseases

Shuaibu Abdullahi Hudu
Najlaa Saadi
Albashir Tahir
Abdulgafar Olayiwola Jimoh
Aliyu Haruna

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1654467

1,956 views

Original Research

Published on 30 Sep 2025

Antimicrobial activity of β-lactam antibiotics against pneumococcal isolates causing pneumococcal disease in adults immediately before and after the COVID-19 pandemic in Spain (2019–2020)

in Pharmacology of Infectious Diseases

Mirella Llamosí
Covadonga Pérez-García
Aída Úbeda
Erick J. Vidal-Alcántara
Inés Pareja-Cerbán
Elena Gómez-Rubio
Pilar Coronel
Juan Carlos Sanz
Mirian Domenech
Julio Sempere

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1658431

1,092 views

Original Research

Accepted on 29 Sep 2025

Comparative in vitro Susceptibility of Clinical Leishmania Isolates to Miltefosine and Oleylphosphocholine

in Pharmacology of Infectious Diseases

Ali Khamesipour
minoo Tasbihi
Akram Mir Amin Mohammadi
Jodie Dixon
David J Clark
Henry M Staines
Sanjeev Krishna
Vanessa Yardley
Simon L Croft
Neal Alexander

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1688856

363 views

Review

Published on 29 Sep 2025

Antibiotic-sparing strategies for multidrug-resistant organism (MDRO) infections

in Pharmacology of Infectious Diseases

Shuai Geng
Qing Tang
Ning Shi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1653424

2,132 views

Original Research

Accepted on 26 Sep 2025

Febuxostat may decrease the incidence of COVID-19 infection among patients with gout: A Retrospective Cohort Study

in Pharmacology of Infectious Diseases

Weijie Wang
Shiow-Ing Wang
Yang Cheng
Xinchang Wang
Yongsheng Fan
James Cheng-Chung Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1654173

575 views

Review

Published on 26 Sep 2025

Small nucleic acid drugs-the dawn of functional cure of chronic hepatitis B

in Pharmacology of Infectious Diseases

Lu Zhang
Yu Cao
Sijing Zhuang
Jingjing Sun
Qiao Tong
Jianjun Xi
Shourong Liu
Rangxiao Zhuang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1633001

2,450 views

Original Research

Published on 25 Sep 2025

Topical delivery of meropenem via spanlastic carbopol gel: in-vitro studies and in-vivo application in pressure ulcers

in Pharmacology of Infectious Diseases

Shadwa Abdelfattah
Fatma Mohamed Mady
Hatem A. Sarhan
Hazim O. Khalifa
Hamada Hashem
Hesham Hassan
Abdullah Alkhammash
Safy Hadiya
Reham Ali Ibrahem
Milad Reda Qelliny

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1672677

1,486 views