Frontiers in Pharmacology | Pharmacology of Infectious Diseases

Original Research

Published on 05 Sep 2025

Synthesis and biological activity evaluation of a novel pleuromutilin derivative 22-((2-methyl-1-(1H-pyrrole-2-carboxamido)propan-2-yl)thio)-deoxypleuromutilin

in Pharmacology of Infectious Diseases

Zhun Li
Danqian Ma
Chang Liu
Zhe Qin
Lixia Bai
Wenbo Ge
Xiao Xu
Jianyong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1657973

368 views

Original Research

Published on 04 Sep 2025

Effectiveness of infection control measures informed by a modified Blue-Carba test in reducing rectal carriage of carbapenemase-producing bacteria in general wards: a prospective interrupted time series study

in Pharmacology of Infectious Diseases

Maximiliano Gabriel Castro
Fernanda Argarañá
Carla Bernasconi
Leticia Margenet
Ana Paula Amato
Joaquín Ignacio Coduri Anthonioz Blanc
Erwin Alexander Rottoli
Manuel Protto
Macarena Vicino
María José Sadonio

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1584646

896 views

Systematic Review

Published on 02 Sep 2025

Efficacy and safety of nebulized drugs in the treatment of non-severe mycoplasma pneumoniae pneumonia in children - a network meta-analysis

in Pharmacology of Infectious Diseases

Li Zeng
Hanlin Ye
Qiu Zhang
Ting Xu
Hong Xu
Dan Bi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1587152

545 views

Original Research

Accepted on 01 Sep 2025

Real-world correlation between therapeutic drug monitoring and clinical outcomes of the antifungal drug posaconazole: a single-center retrospective cohort study

in Pharmacology of Infectious Diseases

Qiaoyan Yi
Lin Dong
Peng Wang
Yinpin Shi
Yilei Yang
Zhonghua Dong
Siwen Li
Yan LI
Xin Huang
Jinjuan Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592767

368 views

Editorial

Accepted on 01 Sep 2025

Beyond Traditional Antibiotics: Innovations in Biologics, Chemical Modulators, and Microbiome Manipulation

in Pharmacology of Infectious Diseases

Anutthaman Parthasarathy

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1679268

362 views

Editorial

Published on 01 Sep 2025

Editorial: Natural products and nanotechnology: next-generation therapies for infectious diseases

in Pharmacology of Infectious Diseases

Dolores R. Serrano
Edilene Oliveira Silva
Vasundhra Bhandari

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1682331

509 views

Original Research

Accepted on 28 Aug 2025

The Role of Curcumin in Modulating Nutritional Status and Susceptibility to Mycoplasma pneumoniae Infection in Children

in Pharmacology of Infectious Diseases

Chun-Jing Liu
Wei Liu
Hong-Xiu Yang
Li-Hua Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1651875

283 views

Original Research

Published on 22 Aug 2025

Identification of gene signatures and potential pharmaceutical candidates linked to COVID-19-related depression based on gene expression profiles

in Pharmacology of Infectious Diseases

Shaojun Chen
Yiyuan Luo
Lihua Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1562774

973 views

Review

Published on 21 Aug 2025

Broad-spectrum therapeutic potential of 4-phenylbutyrate in neurological and systemic diseases of viral and non-viral origin

in Pharmacology of Infectious Diseases

Fatima Bobat
David Wu
Ethan Tu
Divya Kapoor
Pankaj Sharma
Joseph S. Adams
Chima Orameh
Tejabhiram Yadavalli
Abhijit Date
Deepak Shukla

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1621590

941 views

Original Research

Published on 20 Aug 2025

In vitro assessment of Brazilian red propolis against mycobacteria: antibacterial potency, synergy, inhibition of biofilm formation, and intramacrophage effects

in Pharmacology of Infectious Diseases

S. B. Martins
S. C. Teixeira
G. de Souza
Bader Y. Alhatlani
Emad M. Abdallah
S. R. Ambrosio
T. S. Silva
J. K. Bastos
M. H. Tanimoto
B. F. Barbosa

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1630134

915 views

Original Research

Accepted on 12 Aug 2025

Antibacterial and Wound Healing Effects of PEG-Coated Ciprofloxacin-Loaded ZIF-8 Nanozymes Against Ciprofloxacin-Resistant Pseudomonas aeruginosa Taken from Burn Wounds

in Pharmacology of Infectious Diseases

Mohadeseh Pahlevani
Masoumeh Beig
Seyed Mahmoud Barzi
Morvarid Shafiei
Mohsen Chiani
Aria Sohrabi
Mohammad Sholeh
Shaghayegh Nasr

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1556335

255 views

Systematic Review

Published on 07 Aug 2025

Flavonoids in the treatment of Leishmania amazonensis: a review of efficacy and mechanisms

in Pharmacology of Infectious Diseases

Vinicius Lopes Lessa
Guilherme Drescher
Gustavo Gonçalves
João Carlos Baptista Lopes
Rafael Felipe da Costa Vieira
Fabiano Borges Figueiredo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1642005

1,014 views

Study Protocol

Published on 07 Aug 2025

Continuous infusion versus intermittent dosing of ceftazidime/avibactam in critically ill patients with Klebsiella pneumoniae OXA-48 or Pseudomonas aeruginosa infections: a single-center randomized open-label trial (ZAVICONT). Rationale and design

in Pharmacology of Infectious Diseases

Mirna Momčilović
Ivan Šitum
Ante Erceg
Marko Siroglavić
Mila Lovrić
Laura Nižić Nodilo
Anita Hafner
Jasmina Lovrić
Petra Turčić
Dora Fabijanović

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1618987

1,008 views

Original Research

Published on 06 Aug 2025

Durability and effectiveness of dual vs. triple therapy and tablet simplification in ART: findings from the Italian MOSAICO study

in Pharmacology of Infectious Diseases

Daniele Mengato
Giacomo Berti
Andrea Francavilla
Silvia Michielan
Linda Cappellazzo
Laura Agnoletto
Maria Chiara Silvani
Marco Chiumente
Dario Gregori
Maria Mazzitelli

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1633968

865 views

Systematic Review

Accepted on 31 Jul 2025

Prevalence and mortality of acute kidney injury in scrub typhus: A systematic review and metaanalysis

in Pharmacology of Infectious Diseases

Prakasini Satapathy PhD, MPH
Abhay M Gaidhane Gaidhane
Nasir Vadia
Soumya V Menon
Kattela Chennakesavulu
Rajashree Panigrahi
Suraj Tiwari
Sanjit Sah
Riyaz Khan P
S Govinda Rao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1604656

293 views

Systematic Review

Published on 31 Jul 2025

Exploring the clinical effects of Andrographis paniculata-derived compounds, its extract, or derivatives for the treatment of COVID-19: a systematic review and meta-analysis

in Pharmacology of Infectious Diseases

Peerapong Prabhakornritta
Neti Waranuch
Anjana Fuangchan
Kantapich Srikham
Kansak Boonpattharatthiti
Cindy Barnig
Siwaporn Boonyasuppayakorn
Tasana Pitaksuteepong
Parvapan Bhattarakosol
Brice Moulari

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1598255

1,058 views