Frontiers in Pharmacology | Predictive Toxicology

Review

Published on 09 Jan 2025

Role of copper homeostasis and cuproptosis in heart failure pathogenesis: implications for therapeutic strategies

in Predictive Toxicology

Zhichao Liu
Yongkang Gan
Zhen Shen
Siqi Cai
Xizhen Wang
Yong Li
Xiaofeng Li
Huanjie Fu
Jinhong Chen
Ningcen Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1527901

1,894 views

Case Report

Published on 07 Jan 2025

Ceftriaxone-induced hemolytic anemia managed successfully in a 54-year-old woman: a case report and literature review

in Predictive Toxicology

Liqian Zhang
Wenfeng Huang
Jiakai Xu
Yunxing Li
Jihong Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1505366

1,258 views
1 citation

Original Research

Published on 06 Jan 2025

CPT1 deficiency blocks autophagic flux to promote lipid accumulation induced by co-exposure to polystyrene microplastic and cadmium

in Predictive Toxicology

Zhixuan Chen
Huayi Qu
Jian Sun
Tao Wang
Yan Yuan
Jianhong Gu
Jianchun Bian
Zongping Liu
Hui Zou

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1533188

1,371 views
1 citation

Original Research

Accepted on 02 Jan 2025

Drug-induced dermatomyositis: a pharmacovigilance study of the FDA adverse event reporting system

in Predictive Toxicology

Jianing Bi
Hanzhang Xie
Yixuan Yang
Qiaochu Chen
Bingnan Cui
ZhanShuo Xiao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1526836

314 views

Original Research

Published on 17 Dec 2024

Quantitative study on hepatic genotoxicity of neodymium and its molecular mechanisms based on Benchmark Dose method

in Predictive Toxicology

Ning Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1484111

1,082 views
1 citation

Original Research

Published on 28 Nov 2024

Integration of genomics, clinical characteristics and baseline biological profiles to predict the risk of liver injury induced by high-dose methotrexate

in Predictive Toxicology

Chenquan Lin
Rui Ma
Xiao Zeng
Bikui Zhang
Ting Cao
Shimeng Jiao
Hui Chen
Yifang He
Mouze Liu
Hualin Cai

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1423214

1,458 views

Case Report

Published on 26 Nov 2024

Case Report: Sudden death caused by methylene chloride poisoning

in Predictive Toxicology

Ruikai Shang
Qiaoxin Tian
Yuru Liu
Hongyu Liu
Xiangxing Zhang
Mengdi Shi
Xiangdong Jian
Qilu Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1471744

1,314 views

Perspective

Published on 26 Nov 2024

Mitigating Paxlovid™-induced drug‒drug interaction toxicity: an in silico insight

in Predictive Toxicology

Giang H. Ta
Max K. Leong

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1496630

868 views

Original Research

Published on 11 Nov 2024

Delayed immune-related adverse events profile associated with immune checkpoint inhibitors: a real-world analysis

in Predictive Toxicology

Yana Yang
Linman Li
Jing Tian
Linwen Ma
Yaoxin Wu
Qian Luo
Yan Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1453429

2,267 views
4 citations

Original Research

Published on 05 Nov 2024

DDIT4/mTOR signaling pathway mediates cantharidin-induced hepatotoxicity and cellular damage

in Predictive Toxicology

Wenchao Tang
Yue Pan
Can Zhu
Didong Lou
Fang Peng
Qin Shi
Yuanyuan Xiao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1480512

1,756 views

Original Research

Published on 29 Oct 2024

Modelling hemodynamics regulation in rats and dogs to facilitate drugs safety risk assessment

in Predictive Toxicology

Christopher J. Morris
Michael G. Rolf
Linda Starnes
Inmaculada C. Villar
Amy Pointon
Holly Kimko
Giovanni Y. Di Veroli

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1402462

1,311 views
1 citation

Original Research

Published on 29 Oct 2024

Osteonecrosis of the jaw in patients with clear cell renal cell carcinoma treated with targeted agents: a case series and large-scale pharmacovigilance analysis

in Predictive Toxicology

Shuyun Wang
Rui Zhang
Song Wang
Qian Guo
Donghong Yin
Yan Song
Xianhua She
Xuyan Wang
Jinju Duan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1309148

2,290 views

Original Research

Published on 23 Oct 2024

Identification of human pregnane X receptor antagonists utilizing a high-throughput screening platform

in Predictive Toxicology

Caitlin Lynch
Ryan Margolis
Jacob Niebler
Jameson Travers
Srilatha Sakamuru
Tongan Zhao
Carleen Klumpp-Thomas
Ruili Huang
Menghang Xia

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1448744

1,689 views

Original Research

Published on 18 Oct 2024

Monocrotaline-mediated autophagy via inhibiting PI3K/AKT/mTOR pathway induces apoptosis in rat hepatocytes

in Predictive Toxicology

Yazhou Guo
Yang Yuan
Ruibo Wang
Jun Bai
Yanqing Jia
Xinxin Qiu
Huafeng Niu
Long Li
Yan Luo
Baoyu Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1499116

1,398 views
1 citation

Original Research

Published on 03 Oct 2024

Development and validation of PBPK models for genistein and daidzein for use in a next-generation risk assessment

in Predictive Toxicology

A. Najjar
D. Lange
C. Géniès
J. Kuehnl
A. Zifle
C. Jacques
E. Fabian
N. Hewitt
A. Schepky

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1421650

2,176 views
3 citations

Review

Published on 24 Sep 2024

Apoptosis, autophagy, ferroptosis, and pyroptosis in cisplatin-induced ototoxicity and protective agents

in Predictive Toxicology

Dingyuan Dai
Chao Chen
Chen Lu
Yu Guo
Qi Li
Chen Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1430469

3,402 views
5 citations