Frontiers in Oncology | Molecular and Cellular Oncology

Original Research

Published on 25 Jun 2025

Untargeted metabolomics revealed urinary metabolic pattern for discriminating prostate cancer from benign prostatic hyperplasia in Chinese participants

in Molecular and Cellular Oncology

Chenye Tang
Xiao Guo
Qian Zou
Xinghao Wang
Jian Sheng
Dan Shen
Chun Sun
Shuo Li
Ruilin Shen

Frontiers in Oncology

doi 10.3389/fonc.2025.1604169

1,652 views

Original Research

Published on 25 Jun 2025

RBP7 knockdown inhibits proliferation of human hepatocellular carcinoma and activates the p38 MAPK pathway

in Molecular and Cellular Oncology

Jinhai Li
Huawei Zhai
Fujing Cai
Xian Zhang
Yu Zhou
Shuqun Li
Huachun Song
Haifeng Zhang
Guangzheng Sun
Minghui Zhu

Frontiers in Oncology

doi 10.3389/fonc.2025.1592616

1,429 views

Original Research

Published on 24 Jun 2025

CHMP6 as a novel prognostic biomarker in bladder cancer: insights from a comprehensive cell death-related gene risk model

in Molecular and Cellular Oncology

Wei Ning
Yan-Ru Yang
Chen-Xu Wu
Yue Hou
Zhi-Wei Liu
Chang-Bin Yang

Frontiers in Oncology

doi 10.3389/fonc.2025.1564826

2,213 views

Original Research

Published on 24 Jun 2025

p53 enhances elesclomol-Cu-induced cuproptosis in hepatocellular carcinoma via FDXR-mediated FDX1 upregulation

in Molecular and Cellular Oncology

Xiao Liu
Honglin Qu
Jingmin Li
Xuhong Sun
Zhenlin Wang
Dong Wang
Xianyong Bai
Xiaoyan Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1584811

3,613 views
1 citation

Original Research

Published on 23 Jun 2025

CD16 and Siglec expression refine the phenotypic heterogeneity of steady-state myeloid-derived suppressor cells

in Molecular and Cellular Oncology

Chris D. St. Laurent
Zeinab Jame-Chenarboo
Alyssa E. Beck
Stacey Stubblefield
Shiteng Duan
Darren Sigal
Matthew S. Macauley

Frontiers in Oncology

doi 10.3389/fonc.2025.1570121

2,022 views
1 citation

Original Research

Published on 23 Jun 2025

PP1γ promotes esophageal squamous cell carcinoma progression through the PP1γ/YAP1/SOX2 axis

in Molecular and Cellular Oncology

Juan Du
Li Liu
Shutao Zheng
Chenglu Dai
Jingyu Liu
Wei Zhang
Hongwei Pu
Jing Xue

Frontiers in Oncology

doi 10.3389/fonc.2025.1586679

1,472 views

Original Research

Published on 23 Jun 2025

Hsa_circ_0018909 promotes non-small cell lung cancer by directly regulating hsa-miR-513b-5p

in Molecular and Cellular Oncology

Qi Liu
Yong-Kui Yu
Hao-Miao Li
Wei Wang
Jing Xu

Frontiers in Oncology

doi 10.3389/fonc.2025.1542742

1,380 views

Original Research

Published on 20 Jun 2025

MiR-221, miR-320a, miR133a, and miR-133b as potential biomarkers in leiomyosarcoma

in Molecular and Cellular Oncology

Mst Nasrin Akhtar
Annabell Walter
Kathrin Katenkamp
Yuan Chen
Thomas Lehmann
Wolfram Weschenfelder
Christian Spiegel
Matthias Vogt
Gunther O. Hofmann
Andreas Hochhaus

Frontiers in Oncology

doi 10.3389/fonc.2025.1577859

1,576 views

Review

Published on 19 Jun 2025

Research progress on FOXM1 in ovarian cancer diagnosis and therapeutics

in Molecular and Cellular Oncology

Xiao-Qing Tan
Ai-Ying Guo
Li-Fei Zheng
Jun Xiong

Frontiers in Oncology

doi 10.3389/fonc.2025.1598868

2,415 views
3 citations

Case Report

Published on 18 Jun 2025

Case Report: Metastatic colorectal cancer with ALK–CEP44 fusion and rapid resistance development

in Molecular and Cellular Oncology

Silvan Hofmann
Claudine Egger
Silke Potthast
Martin Zoche
Andreas Wicki
Tarun Mehra

Frontiers in Oncology

doi 10.3389/fonc.2025.1613235

1,863 views

Review

Published on 17 Jun 2025

Neutrophil extracellular traps and cannabinoids: potential in cancer metastasis

in Molecular and Cellular Oncology

Izabela Krauze
Beata Greb-Markiewicz
Anna Kłopot
Kamila Maciejewska
Michał Bryk
Małgorzata Krzystek-Korpacka

Frontiers in Oncology

doi 10.3389/fonc.2025.1595913

3,772 views
2 citations

Case Report

Published on 12 Jun 2025

Neuroepithelial tumors of the central nervous system with EWSR1::PATZ1 fusion: a case report and literature review

in Molecular and Cellular Oncology

João Felipe Lima Feldmann
João Henrique Lima Feldmann
Felipe Sales Canedo
Felipe Cicci Farinha Restini
Romulo Loss Mattedi
Luiz Guilherme Cernaglia A. de Lima
Olavo Feher

Frontiers in Oncology

doi 10.3389/fonc.2025.1604479

2,317 views

Original Research

Published on 10 Jun 2025

Prognostic significance of preoperative neutrophil-to-lymphocyte ratio in lung carcinoid patients after receiving curative surgery. A multicentre study

in Molecular and Cellular Oncology

Nicola Tamburini
Beatrice Aramini
Ilaria Potenza
Francesco Bagolini
Danila Azzolina
Fares Shamshoum
Federico Rea
Franco Stella
Giampiero Dolci
Enrica Pellizzer

Frontiers in Oncology

doi 10.3389/fonc.2025.1585433

1,466 views

Review

Published on 09 Jun 2025

Exploring a new direction in targeted cancer therapy through hyperbaric oxygen therapy combined with biomedical engineering techniques

in Molecular and Cellular Oncology

Shuhao Mei
Yuyin Han
Hailian Yi
Yuling Gao
Yong Liu
Xiaoyang Gong

Frontiers in Oncology

doi 10.3389/fonc.2025.1580515

5,296 views
1 citation

Original Research

Published on 05 Jun 2025

Digital spatial profiling identifies phospho-JNK as a biomarker for early risk stratification of aggressive prostate cancer

in Molecular and Cellular Oncology

Samaneh Eickelschulte
Adam Kaczorowski
Florian Janke
Anja Lisa Riediger
Olga Lazareva
Sarah Böning
Glen Kristiansen
Constantin Schwab
Albrecht Stenzinger
Holger Sültmann

Frontiers in Oncology

doi 10.3389/fonc.2025.1572299

2,150 views

Editorial

Published on 05 Jun 2025

Editorial: Overcoming therapeutic resistance in head and neck squamous cell carcinoma

in Molecular and Cellular Oncology

Souvick Roy
Prakriti Sen
Madhabananda Kar
Birendranath Banerjee

Frontiers in Oncology

doi 10.3389/fonc.2025.1611819

1,312 views

Review

Published on 04 Jun 2025

Research progress on the cross-regulation between ferroptosis and immunogenic cell death in tumor micro-environment

in Molecular and Cellular Oncology

Weitao Liu
Yichen Jing
Yang Chen
Han Sun
Wenbo Xu
Ruihan Liang
Wanglin Liu
Zengyu Zhang
Huiping Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1581951

4,337 views
4 citations

Review

Published on 03 Jun 2025

Current trends in theranostic applications of extracellular vesicles in cancer

in Molecular and Cellular Oncology

Yazan Almasry
Fayrouz Mustafa
Mohammed Alfuwais
Sara AlNachef
Hager Mohamed
Nusaibah S. Gaber
Mohammed Imran Khan
Islam M. Saadeldin
Ahmed Yaqinuddin

Frontiers in Oncology

doi 10.3389/fonc.2025.1592006

3,649 views

Original Research

Published on 03 Jun 2025

IGF2BP3 enhances ferroptosis resistance in colon cancer by stabilizing SLC7A11 and is regulated by miR-98-5p

in Molecular and Cellular Oncology

Yaya Sun
Qingwei Liu
Junjie Wu
Guangqing Jiang
Hongzhou Shi
Yihong Zhang
Yanxuan Ling
Weimin Sun
Xin Shi
Congxing Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1576895

2,750 views
1 citation

Original Research

Published on 29 May 2025

METTL3-mediated SNHG1 m6A modification promotes proliferation and migration through transcriptional regulation of WDR74 in osteosarcoma

in Molecular and Cellular Oncology

Guanzhen Qiu
Yuxin Bao
Yuanzhuang Zhang
Yeqiu Xu
Tianhua Qiao
Chenghao Li
Hanjie Zhai
Zhenjun Chen
Fu Ren
Yong Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1529657

2,192 views
2 citations

Mini Review

Published on 29 May 2025

Senescence-associated secretory phenotype in lung cancer: remodeling the tumor microenvironment for metastasis and immune suppression

in Molecular and Cellular Oncology

Chen Chen
Ji Chen
Yanling Zhang
Qijun Zhang
Haixia Shi

Frontiers in Oncology

doi 10.3389/fonc.2025.1605085

4,406 views
6 citations

Editorial

Published on 28 May 2025

Editorial: Repurposed drugs targeting cancer signaling pathways: clinical insights to improve oncologic therapies, volume II

in Molecular and Cellular Oncology

Alma D. Campos-Parra
Gerardo Leyva-Gomez
Teresita Padilla-Benavides

Frontiers in Oncology

doi 10.3389/fonc.2025.1628842

1,717 views

Original Research

Published on 28 May 2025

Comprehensive simulations of intracellular electric fields during exposure to tumor treating fields

in Molecular and Cellular Oncology

Kaida Liu
Ping Dai
Zirong Liu
Haohan Fang
Xing Li
Wei Gao

Frontiers in Oncology

doi 10.3389/fonc.2025.1520504

1,203 views

Case Report

Published on 23 May 2025

Extra-skeletal Ewing sarcoma in a 63-year-old female with a history of triple-negative breast cancer: a case report and literature review

in Molecular and Cellular Oncology

Man Kit Ho
Golnesa Safavi
Won Jin Jeon
Evelyn Mendoza

Frontiers in Oncology

doi 10.3389/fonc.2025.1545896

2,210 views

3,127 articles

articles

Untargeted metabolomics revealed urinary metabolic pattern for discriminating prostate cancer from benign prostatic hyperplasia in Chinese participants

RBP7 knockdown inhibits proliferation of human hepatocellular carcinoma and activates the p38 MAPK pathway

CHMP6 as a novel prognostic biomarker in bladder cancer: insights from a comprehensive cell death-related gene risk model

p53 enhances elesclomol-Cu-induced cuproptosis in hepatocellular carcinoma via FDXR-mediated FDX1 upregulation

CD16 and Siglec expression refine the phenotypic heterogeneity of steady-state myeloid-derived suppressor cells

PP1γ promotes esophageal squamous cell carcinoma progression through the PP1γ/YAP1/SOX2 axis

Hsa_circ_0018909 promotes non-small cell lung cancer by directly regulating hsa-miR-513b-5p

MiR-221, miR-320a, miR133a, and miR-133b as potential biomarkers in leiomyosarcoma

Research progress on FOXM1 in ovarian cancer diagnosis and therapeutics

Case Report: Metastatic colorectal cancer with ALK–CEP44 fusion and rapid resistance development

Neutrophil extracellular traps and cannabinoids: potential in cancer metastasis

Neuroepithelial tumors of the central nervous system with EWSR1::PATZ1 fusion: a case report and literature review

Prognostic significance of preoperative neutrophil-to-lymphocyte ratio in lung carcinoid patients after receiving curative surgery. A multicentre study

Exploring a new direction in targeted cancer therapy through hyperbaric oxygen therapy combined with biomedical engineering techniques

Digital spatial profiling identifies phospho-JNK as a biomarker for early risk stratification of aggressive prostate cancer

Editorial: Overcoming therapeutic resistance in head and neck squamous cell carcinoma

Research progress on the cross-regulation between ferroptosis and immunogenic cell death in tumor micro-environment

Current trends in theranostic applications of extracellular vesicles in cancer

IGF2BP3 enhances ferroptosis resistance in colon cancer by stabilizing SLC7A11 and is regulated by miR-98-5p

METTL3-mediated SNHG1 m6A modification promotes proliferation and migration through transcriptional regulation of WDR74 in osteosarcoma

Senescence-associated secretory phenotype in lung cancer: remodeling the tumor microenvironment for metastasis and immune suppression

Editorial: Repurposed drugs targeting cancer signaling pathways: clinical insights to improve oncologic therapies, volume II

Comprehensive simulations of intracellular electric fields during exposure to tumor treating fields

Extra-skeletal Ewing sarcoma in a 63-year-old female with a history of triple-negative breast cancer: a case report and literature review